Name | Boc-D-Ala-OH |
Synonyms | Boc-D-Ala-OH BOC-D-Alanine BOC-D-ALANINE N-BOC-D-ALANINE N-ALPHA-T-BOC-D-ALA N-ALPHA-T-BOC-D-ALANINE T-BUTYLOXYCARBONYL-D-ALANINE N-tert-Butoxycarbonyl-D-alanine N-(TERT-BUTOXYCARBONYL)-D-ALANINE N-ALPHA-T-BUTOXYCARBONYL-D-ALANINE N-ALPHA-TERT-BUTYLOXYCARBONYL-D-ALANINE (2R)-2-[(tert-butoxycarbonyl)amino]propanoate |
CAS | 7764-95-6 |
EINECS | 616-484-7 |
InChI | InChI=1/C8H15NO4/c1-5(6(10)11)9-7(12)13-8(2,3)4/h5H,1-4H3,(H,9,12)(H,10,11)/p-1/t5-/m1/s1 |
InChIKey | QVHJQCGUWFKTSE-RXMQYKEDSA-N |
Molecular Formula | C8H15NO4 |
Molar Mass | 189.21 |
Density | 1.2321 (rough estimate) |
Melting Point | 81-84 °C |
Boling Point | 324.46°C (rough estimate) |
Specific Rotation(α) | 26 º (c=2,EtOH) |
Flash Point | 147.9°C |
Solubility | Chloroform, DMSO, Methanol |
Vapor Presure | 6.39E-05mmHg at 25°C |
Appearance | White crystal |
Color | White |
BRN | 2048396 |
pKa | 4.02±0.10(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 26 ° (C=2, AcOH) |
MDL | MFCD00063123 |
Physical and Chemical Properties | White crystalline powder; Insoluble in water and petroleum ether, soluble in ethyl acetate and acetic acid; mp 80- 83 ℃; specific optical rotation [α]20D 24.3 °- 24.7 °(0.5-2.0mg/ml, acetic acid). |
Hazard Symbols | Xn - Harmful |
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
WGK Germany | 3 |
HS Code | 29241990 |
Hazard Class | IRRITANT |
uses | is used for polypeptide synthesis, as amino acid protecting monomer. |
production method | D-alanine was suspended in dioxane solution, the crude product is obtained by acylation reaction with tert-butoxycarbonyl azide and then refined by recrystallization. |