Boc-NH-PEG(3)-COOH

Name	Boc-NH-PEG(3)-COOH
Synonyms	Boc-NH-PEG(3)-COOH Boc-NH-(PEG)4-CH2COOH t-Boc-N-amido-PEG4-CH2CO2H Boc-NH-PEG(3)-COOH(16atoMs) t-boc-N-amido-PEG4-acetic acid 14-(Boc-amino)-3,6,9,12-tetraoxatetradecan-1-oic Acid 2,2-Dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azanonadecan-19-oic acid 5,8,11,14-Tetraoxa-2-azahexadecanedioic acid, 1-(1,1-dimethylethyl) ester
CAS	876345-13-0

Molecular Formula	C15H29NO8
Molar Mass	351.39
Density	1.138±0.06 g/cm3(Predicted)
Boling Point	493.6±40.0 °C(Predicted)
pKa	3.39±0.10(Predicted)
Storage Condition	-20°C
In vitro study	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

biological activity	Boc-NH-PEG4-CH2COOH is a degradable ADC linker, which is used to synthesize degradable antibody conjugated drugs (ADC) ADC linker. Boc-NH-PEG4-CH2COOH is also a PEG-based PROTAC linker, which can be used for PROTAC synthesis.
target	Cleavable Alkyl/ether PEGs
in vitro study	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Last Update：2024-04-09 21:21:28

Product Name: Boc-NH-PEG(3)-COOH Visit Supplier Webpage Request for quotation
CAS: 876345-13-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

Product Name: Boc-NH-PEG(3)-COOH Visit Supplier Webpage Request for quotation
CAS: 876345-13-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

View History

Boc-NH-PEG(3)-COOH

Boc-NH-PEG(3)-COOH Request for Quotation