Boc-beta-(S)-4-bromophenylalanine

Boc-beta-(S)-4-bromophenylalanine - Names and Identifiers

Name	Boc-S-3-Amino-3-(4-bromo-phenyl)-propionic acid
Synonyms	Boc-b-Phe(4-Br)-OH (s)-boc-4-bromo-β-phe-oh BOC-(S)-4-SS-BROMOPHENYLALANINE Boc-4-Bromo-D-beta-phenylalanine Boc-beta-(S)-4-bromophenylalanine Boc-S-3-Amino-3-(4-bromo-phenyl)-propionic acid (S)-N-Boc-3-amino-3-(4-bromophenyl)propanoicacid(e.e.) (S)-3-(4-BROMO-PHENYL)-3-TERT-BUTOXYCARBONYLAMINO-PROPIONIC ACID (3S)-3-(4-bromophenyl)-3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid (S)-3-(Boc-amino)-3-(4-bromophenyl)propionic acid, Boc-4-bromo-D-β-phenylalanine
CAS	261165-06-4

Boc-beta-(S)-4-bromophenylalanine - Physico-chemical Properties

Molecular Formula	C14H18BrNO4
Molar Mass	344.2
Density	1.5311 (rough estimate)
Melting Point	143.8 °C
Boling Point	479.1±40.0 °C(Predicted)
pKa	4.27±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.6500 (estimate)

Boc-beta-(S)-4-bromophenylalanine - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29223900

Boc-beta-(S)-4-bromophenylalanine - Introduction

Boc-S-3-Amino-3-(4-bromo-phenyl)-propionic acid is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
Boc-S-3-Amino -3-(4-bromophenyl) propionic acid is a white or off-white solid. It is a polar molecule with high solubility, soluble in many organic solvents at room temperature, such as dimethyl sulfoxide and dimethyl formamide. The chemical structure of the compound contains the protecting group Boc(tert-butoxycarbonyl), which helps to protect the amino function and provides chemical stability.

Use:
Boc-S-3-Amino -3-(4-bromophenyl) propionic acid is an important intermediate in organic synthesis. It can be used to synthesize biologically active compounds, such as drugs, peptides, polypeptides, etc. This compound can be used by pharmaceutical researchers and synthetic chemists to synthesize compounds that modulate protein function.

Preparation Method:
The method for preparing Boc-S-3-amino -3-(4-bromophenyl) propionic acid generally involves the following steps: First, 4-bromobenzyl alcohol and acrylonitrile are reacted under suitable reaction conditions to form a (4-bromophenyl) propionitrile compound. Subsequently, the nitrile group is reduced to an amino group by hydrogenation reduction or other methods. Finally, esterification reaction was carried out with Boc protecting group as reactant to obtain the final product Boc-S-3-amino -3-(4-bromophenyl) propionic acid.

Safety Information:
Boc-S-3-amino -3-(4-bromophenyl) propionic acid is a low-toxic compound in general. However, as an organic compound, it may cause certain irritation and harm to the human body. Therefore, appropriate safety measures should be taken during use, including wearing protective gloves, glasses and laboratory coats to ensure that the operation is carried out in a well-ventilated environment. At the same time, avoid direct contact with the skin and inhalation of its dust or steam. If any health problems occur, seek medical attention immediately.

Last Update：2024-04-09 21:11:58