Brometazepam
metaclazepam
CAS: 84031-17-4
Molecular Formula: C18H18BrClN2O
Brometazepam - Names and Identifiers
Brometazepam - Physico-chemical Properties
| Molecular Formula | C18H18BrClN2O |
| Molar Mass | 393.71 |
| Density | 1.41±0.1 g/cm3(Predicted) |
| Boling Point | 472.4±45.0 °C(Predicted) |
| pKa | 4.14±0.65(Predicted) |
| Storage Condition | Room Temprature |
| Physical and Chemical Properties | Chemical properties metazepam hydrochloride (Metaclazepam Hydrochlofide):C18H18 BrClN2O?HCI. [61802-93-5]. Crystallized from ethanol, melting point 193-196 ℃. Acute toxicity LD50 mice (mg/kg):1578 oral. |
| Use | Uses benzodiazepine drugs. For antidepressants. |
Brometazepam - Upstream Downstream Industry
| Raw Materials | Dichloromethane 2-Chlorobenzoyl chloride |
Brometazepam - Production method
Compound (I) is acylated with o-chlorobenzoyl chloride to obtain compound (II). Then refluxed with phosphorus oxychloride to obtain a mixture of compound (III) and compound (IV). The mixture is in the presence of sodium methoxide. Refluxed in methanol, all converted to compound (V). Then in dichloromethane, it is brominated in reflux to obtain metazepam.
Last Update：2024-04-09 21:01:54
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CAS: 84031-17-4
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CAS: 84031-17-4
Tel: 18301782025
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Mobile: 18021002903
QQ: 3008007409
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Raw Materials for Brometazepam