Bromo-5-nitrobenzonitrile
2-Bromo-5-nitrobenzonitrile
CAS: 134604-07-2
Molecular Formula: C7H3BrN2O2
Bromo-5-nitrobenzonitrile - Names and Identifiers
| Name | 2-Bromo-5-nitrobenzonitrile |
| Synonyms | Bromo-5-nitrobenzonitrile 2-Bromo-5-nitrobenzonitrile 2-BroMo-5-nitrobenzonitrile 2-BROMO-5-NITROBENZONITRILE Benzonitrile, 2-bromo-5-nitro- 2-Bromo-1-cyano-5-nitrobenzene 1-CYANO-2-BROMO-5-NITROBENZENE |
| CAS | 134604-07-2 |
| InChI | InChI=1/C7H3BrN2O2/c8-7-2-1-6(10(11)12)3-5(7)4-9/h1-3H |
Bromo-5-nitrobenzonitrile - Physico-chemical Properties
| Molecular Formula | C7H3BrN2O2 |
| Molar Mass | 227.01 |
| Density | 1.81±0.1 g/cm3(Predicted) |
| Melting Point | 118-120 °C |
| Boling Point | 321.1±32.0 °C(Predicted) |
| Flash Point | 148°C |
| Vapor Presure | 0.000304mmHg at 25°C |
| Storage Condition | 2-8°C |
| Sensitive | Moisture Sensitive |
| Refractive Index | 1.638 |
Bromo-5-nitrobenzonitrile - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S60 - This material and its container must be disposed of as hazardous waste. |
| UN IDs | 2811 |
| WGK Germany | 3 |
| HS Code | 29269090 |
| Hazard Note | Irritant |
| Hazard Class | 6.1 |
| Packing Group | Ⅲ |
Bromo-5-nitrobenzonitrile - Introduction
2-Bromo-5-nitrobenzonitrile is an organic compound with the chemical formula C7H4BrNO2.
Nature:
2-Bromo-5-nitrobenzonitrile is a solid substance, colorless or light yellow, with a special smell. It has a high melting point and boiling point, insoluble in water, but soluble in many organic solvents, such as ethanol and dimethylformamide. The compound is sensitive to light and should be kept away from light and heat sources.
Use:
2-bromo-5-nitrobenzonitrile is commonly used as a reagent in organic synthesis reactions. It has important applications in drug synthesis, dye synthesis and other organic synthesis fields. Such compounds are commonly used in the preparation of other important organic compounds, such as fluorescent dyes, pesticides and pharmaceutical intermediates.
Preparation Method:
Generally, the preparation method of 2-bromo-5-nitrobenzonitrile is obtained by a substitution reaction of heptanobenzene. The specific preparation method includes reacting heptanobenzene with bromine and nitric acid to form 2-bromo-5-nitrobenzoic acid, which is then converted to 2-bromo-5-nitrobenzonitrile by acyl chlorination and cyanation.
Safety Information:
2-Bromo-5-nitrobenzonitrile is an organic compound with certain toxicity. Its contact or inhalation may cause irritation and damage to human body. Appropriate personal protective equipment such as chemical goggles, protective gloves and protective clothing should be worn during handling. In addition, the compound should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Use should be careful to avoid dust and particles.
Nature:
2-Bromo-5-nitrobenzonitrile is a solid substance, colorless or light yellow, with a special smell. It has a high melting point and boiling point, insoluble in water, but soluble in many organic solvents, such as ethanol and dimethylformamide. The compound is sensitive to light and should be kept away from light and heat sources.
Use:
2-bromo-5-nitrobenzonitrile is commonly used as a reagent in organic synthesis reactions. It has important applications in drug synthesis, dye synthesis and other organic synthesis fields. Such compounds are commonly used in the preparation of other important organic compounds, such as fluorescent dyes, pesticides and pharmaceutical intermediates.
Preparation Method:
Generally, the preparation method of 2-bromo-5-nitrobenzonitrile is obtained by a substitution reaction of heptanobenzene. The specific preparation method includes reacting heptanobenzene with bromine and nitric acid to form 2-bromo-5-nitrobenzoic acid, which is then converted to 2-bromo-5-nitrobenzonitrile by acyl chlorination and cyanation.
Safety Information:
2-Bromo-5-nitrobenzonitrile is an organic compound with certain toxicity. Its contact or inhalation may cause irritation and damage to human body. Appropriate personal protective equipment such as chemical goggles, protective gloves and protective clothing should be worn during handling. In addition, the compound should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Use should be careful to avoid dust and particles.
Last Update：2024-04-09 20:52:54
