Molecular Formula | C21H25BrN2O3 |
Molar Mass | 433.34 |
Melting Point | 214° (dec) |
Specific Rotation(α) | D20 +8.7° (1% in CHCl3) |
Physical and Chemical Properties | Crystallized from isopropanol, melting point 214 ℃ (decomposition). [α]D20 +8.7 (1%, chloroform). Bromovinylfumarate (Brovincamine Fumarate):C21H25BrN2O3?C4H4O4. [84964-12-5]. Melting point 144 ℃. [α]D20 +4.7 (0.388%, water). |
uses | has the effect of accelerating the vertebral artery, internal carotid artery and cerebral blood flow and the vasodilator effect produced by calcium antagonism. It is an agent for improving cerebral circulation and metabolism, and is used for improving various symptoms of sequelae of cerebral infarction and cerebral arteriosclerosis. |
production method | compound (I) is brominated first, followed by alkaline hydrolysis to obtain vincristine bromide. |