C-(4-Trifluoromethyl-pyridin-3-yl)-methylamine

C-(4-Trifluoromethyl-pyridin-3-yl)-methylamine - Names and Identifiers

Name	[4-(Trifluoromethyl)pyridine-3-yl]methylamine
Synonyms	4-(trifluoromethyl)-3-pyridinemethanamine [4-(trifluoromethyl)-3-pyridyl]methanamine 3-Pyridinemethanamine, 4-(trifluoromethyl)- (4-(trifluoromethyl)pyridin-3-yl)methanamine [4-(Trifluoromethyl)pyridine-3-yl]methylamine C-(4-Trifluoromethyl-pyridin-3-yl)-methylamine 1-[4-(Trifluoromethyl)pyridin-3-yl]methanamine
CAS	771580-70-2
InChI	InChI=1/C7H7F3N2/c8-7(9,10)6-1-2-12-4-5(6)3-11/h1-2,4H,3,11H2

C-(4-Trifluoromethyl-pyridin-3-yl)-methylamine - Physico-chemical Properties

Molecular Formula	C7H7F3N2
Molar Mass	176.14
Density	1.294g/cm³
Boling Point	219.199°C at 760 mmHg
Flash Point	86.369°C
Vapor Presure	0.121mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.467

C-(4-Trifluoromethyl-pyridin-3-yl)-methylamine - Introduction

[4-(Trifluoromethyl)pyridine-3-yl]methylamine is an organic compound with the chemical formula C6H6F3N. The following is a description of its nature, use, preparation and safety information:

1. nature:
-Appearance: colorless liquid or white solid;
-Melting point:-2.5°C;
-Boiling point: 147-148°C;
-density: 1.363g/cm³;
-Relative molecular mass: 153.12g/mol.

2. use:
- [4-(Trifluoromethyl)pyridine-3-yl]methylamine is often used as a reagent in organic synthesis;
-It can be used to prepare biologically active compounds, such as drugs and pesticides;
-The compound is used as an intermediate in the chemical industry for the synthesis of other organic compounds.

3. preparation method:
- [4-(Trifluoromethyl)pyridine-3-yl]methylamine can be prepared by various methods, and the following is one of the commonly used methods: First, 4-amino-3-chloropyridine is reacted with trifluoromethyl borate to generate [4-(trifluoromethyl) pyridin-3-yl] methanol, which is then converted into [4-(Trifluoromethyl)pyridine-3-yl]methylamine by dehydration reaction.

4. Safety Information:
- [4-(Trifluoromethyl)pyridine-3-yl]methylamine is irritating and contact with skin, eyes and respiratory tract should be avoided;
-Wear appropriate protective equipment, such as chemical protective gloves, goggles and protective clothing;
-Storage should be sealed and kept away from fire and oxidizing agents.

Please note that proper laboratory practices and safety precautions should be followed when using chemicals.

Last Update：2024-04-09 21:01:54