C-QUINOLIN-5-YL-METHYLAMINE - Names and Identifiers
C-QUINOLIN-5-YL-METHYLAMINE - Physico-chemical Properties
Molecular Formula | C10H10N2
|
Molar Mass | 158.2 |
Density | 1.156±0.06 g/cm3(Predicted) |
Melting Point | 98-100o C |
Boling Point | 314.7±17.0 °C(Predicted) |
Flash Point | 169.912°C |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Vapor Presure | 0mmHg at 25°C |
Appearance | Solid |
Color | Off-White to Pale Yellow |
pKa | 8.57±0.30(Predicted) |
Storage Condition | Hygroscopic, Refrigerator, under inert atmosphere |
Stability | Hygroscopic |
Refractive Index | 1.663 |
C-QUINOLIN-5-YL-METHYLAMINE - Risk and Safety
Hazard Symbols | T - Toxic
|
Risk Codes | 25 - Toxic if swallowed
|
Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
|
Hazard Class | IRRITANT |
C-QUINOLIN-5-YL-METHYLAMINE - Introduction
1-(quinolin-5-yl)methanamine is an organic compound whose molecular formula is C11H11N2 and whose structural formula is 1-(quinolin-5-yl)methanamine. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 1-(quinolin-5-yl)methanamine is white crystal or crystalline powder.
-Solubility: Its solubility in water is low, but it is soluble in organic solvents such as methanol and dichloromethane.
-Melting point: 1-(quinolin-5-yl) The melting point of methanamine is about 95-99°C.
Use:
-Chemical reagent: It is often used as an important reagent in organic synthesis, such as synthetic routes for constructing complex organic molecules.
-Drug research: It is also widely used in the field of drug research to prepare biologically active compounds.
Preparation Method:
The preparation method of 1-(quinolin-5-yl)methanamine can be carried out by the following steps:
1. Synthesis quinolin-5-ylmethanol: 5-formylquinoline is reacted with methanol to obtain quinolin-5-ylmethanol.
2. aminomethylation reaction: quinolin-5-ylmethanol is heated with carbamate (ammoniumformate) and hydrogen to obtain 1-(quinolin-5-yl)methanamine.
Safety Information:
- 1-(quinolin-5-yl)methanamine in the case of careful operation can generally be handled safely.
-Avoid inhaling, chewing, swallowing or touching the skin during use. Wear appropriate protective equipment, such as gloves and safety glasses.
-During storage, it should be kept away from ignition, oxidants and other flammable materials, and stored in a dry and cool place.
-If the substance is ingested or inhaled, seek medical advice immediately and bring the package or label for your doctor's reference.
Please note that the above information is for reference only. When using or handling any chemical, follow appropriate safety practices and consult professional advice.
Last Update:2024-04-09 15:17:58