C11641
3',4'-Anhydrovinblastine
CAS: 38390-45-3
Molecular Formula: C46H56N4O8
C11641 - Names and Identifiers
| Name | 3',4'-Anhydrovinblastine |
| Synonyms | C11641 F 81097 ANHYDROVINBLASTINE Anhydrovinblastine Vinblastineanhydrous 3',4'-Dehydrovinblastine 3',4'-Anhydrovinblastine 3',4'-anhydrovinblastine Anhydrovincaleukoblastine 3',4'-Dehydroisoleurosine 3',4'-Didehydrovinblastine 3',4'-Didehydroisoleurosine 3',4'-Didehydro-4'-deoxyvincaleukoblastine 3',4'-Didehydro-4'-deoxuvincaleukoblastine Vincaleukoblastine, 3',4'-didehydro-4'-deoxy- methyl (2beta,3beta,4beta,5alpha,19alpha)-4-(acetyloxy)-15-[(7R,9S)-5-ethyl-9-(methoxycarbonyl)-1,4,7,8,9,10-hexahydro-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate methyl (2beta,3beta,4beta,5alpha,12beta,19alpha)-4-(acetyloxy)-15-[(7S,9S)-5-ethyl-9-(methoxycarbonyl)-1,4,7,8,9,10-hexahydro-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate |
| CAS | 38390-45-3 |
| InChI | InChI=1/C46H56N4O8/c1-8-28-21-29-24-45(41(52)56-6,37-31(15-19-49(25-28)26-29)30-13-10-11-14-34(30)47-37)33-22-32-35(23-36(33)55-5)48(4)39-44(32)17-20-50-18-12-16-43(9-2,38(44)50)40(58-27(3)51)46(39,54)42(53)57-7/h10-14,16,21-23,29,38-40,47,54H,8-9,15,17-20,24-26H2,1-7H3/t29-,38+,39-,40-,43-,44-,45+,46+/m1/s1 |
C11641 - Physico-chemical Properties
| Molecular Formula | C46H56N4O8 |
| Molar Mass | 792.96 |
| Density | 1.35±0.1 g/cm3(Predicted) |
| pKa | 11.36±0.60(Predicted) |
| Refractive Index | 1.67 |
C11641 - Reference Information
| product description | dehydrated vinblastine is an important raw material for the preparation of vinorelbine and its medicinal salts, and is of great significance to the chemical synthesis of vinorelbine tartrate. |
| product use | devinblastine is one of the mainstream anti-tumor drugs under development with excellent effect. its efficacy mainly inhibits microtubule formation and promotes tumor cell apoptosis by combining with tubulin monomer during cell mitosis G2, it is used for the treatment of non-small cell carcinoma, breast cancer, ovarian cancer, soft tissue and visceral metastases and lymphoma. In addition, dehydrated vinblastine can also be used as an intermediate in the synthesis of vinorelbine. |
Last Update：2024-04-10 22:29:15
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