Name | Vitexin-2-O-rhamnoside |
Synonyms | C12628 2-O-Rhamnosylvitexin VITEXIN-4'-RHAMNOSIDE Vitexin 2''-rhamnoside Vitexin-2-O-rhamnoside VITEXIN-2''-O-RHAMNOSIDE dihydroxy-2-(4-hydroxyphenyl)- Vitexin 2''-o-beta-L-rhamnoside mannopyranosyl)-β-D-glucopyranosyl]-5,7- 4H-1-Benzopyran-4-one,8-[2-O-(6-deoxy-α-L- (1S)-1,5-anhydro-2-O-(6-deoxy-alpha-L-mannopyranosyl)-1-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl]-D-glucitol |
CAS | 64820-99-1 |
InChI | InChI=1/C27H30O14/c1-9-19(33)21(35)23(37)27(38-9)41-26-22(36)20(34)16(8-28)40-25(26)18-13(31)6-12(30)17-14(32)7-15(39-24(17)18)10-2-4-11(29)5-3-10/h2-7,9,16,19-23,25-31,33-37H,8H2,1H3/t9-,16+,19-,20+,21+,22-,23+,25-,26+,27-/m0/s1 |
Molecular Formula | C27H30O14 |
Molar Mass | 578.52 |
Density | 1.74±0.1 g/cm3(Predicted) |
Melting Point | 215°C |
Boling Point | 898.8±65.0 °C(Predicted) |
Flash Point | 299.4°C |
Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
Vapor Presure | 9.4E-35mmHg at 25°C |
Appearance | Yellow powder |
Color | Light Yellow to Yellow |
pKa | 6.21±0.40(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Stability | Unstable in solution |
Refractive Index | 1.751 |
MDL | MFCD00143627 |
Physical and Chemical Properties | Yellow crystalline powder, easily soluble in methanol, derived from hawthorn leaves, Rosaceae Hawthorn plants. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10-21 |
HS Code | 29389090 |
Reference Show more | 1. Huang Qiumei, Xu Shuyu, eyanni et al. Simultaneous determination of 15 components in Jinli ganmao tablets by UPLC-MS/MS [J]. Journal of Pharmaceutical Analysis 2017(08):1453-1460. 2. Yang Xiaobo, Wang Rongfang, Jia Yanan, etc. Determination of nine phenolic compounds in hawthorn leaves by high performance liquid chromatography [J]. Science and Technology of food industry, 2017, 38(010):62-66. 3. Shi Xiaochen, Liu Hongyan, Liu Qian, et al. Determination of seven components in Hawthorn by one-Test multi-evaluation method [J]. Chinese herbal medicine 2019(1):116-121. 4. Yang Pei. Study on the transfer method of near infrared quantitative model of moisture in fluidized bed granulation process [D]. Beijing University of Chinese Medicine, 2020. 5. [IF = 5.279] Yong Sun et al."qualitative and Quantitative Analysis of Phenolics in tetrastigma hemsleyanum and Their antioxidant and antiproliferative Activities." J Agr Food Chem. 2013;61(44):10507-10515 6. [IF = 4.142] Tao Yi et al."Ultrafiltration coupled with high-performance liquid chromatography and quadrupole-time-of-flight mass spectrometry for screening lipase binders from different extracts of Dendrobium officinale."Anal Bioanal Chem. 2015 Aug;407(20):6081-6093 7. [IF=4.098] Chunlin Li et al."Discrimination of white teas produced from fresh leaves with different maturity by near-infrared spectroscopy."Spectrochim Acta A. 2020 Feb;227:117697 8. [IF=3.373] Yiyuan Luo et al."Quality evaluation of Tetrastigma hemsleyanum different parts based on quantitative analysis of 42 bioactive constituents combined with multivariate statistical analysis."PHYTOCHEMICAL ANALYSIS. 2022 Apr 05 |
biological activity | Vitexin-2 "-O-rhamnoside is a major flavonoid glycoside compound in Cratagus pinnatifida Bge, which has a protective effect on H2O2-mediated oxidative stress injury and can be used in the study of cardiovascular diseases. |
chemical properties | yellow crystalline powder, soluble in methanol, derived from hawthorn leaf, Rosaceae hawthorn plant mountain red. |
use | used for content determination/identification/pharmacological experiments, etc. Pharmacological effects: Vitexin rhamnoside has a concentration-dependent relaxation effect on isolated arterial rings. This effect is produced in an endothelium-dependent and endothelium-independent manner, and has the pharmacological effects of some calcium antagonists. It can be used for the preparation of drugs for the treatment of cardiovascular and cerebrovascular diseases. Standard for analysis of herbal products. |