C90104

C90104 - Names and Identifiers

Name	7-Chloro-1,2,3,4-tetrahydroisoquinoline
Synonyms	C90104 7-Chloro-1,2,3,4-tetrahydroisoquinoline 7-CHLORO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE 7-Chloro-1,2,3,4-Tetrahydro-Isoquinoline Isoquinoline,7-chloro-1,2,3,4-tetrahydro- 7-Chloro-1,2,3,4-tetrahydro-isoquinoline 1HCl salt
CAS	82771-60-6

C90104 - Physico-chemical Properties

Molecular Formula	C9H10ClN
Molar Mass	167.64
Density	1.162±0.06 g/cm3(Predicted)
Melting Point	214-217 °C(Solv: ethanol (64-17-5))
Boling Point	267.7±40.0 °C(Predicted)
Appearance	Solid
pKa	9.15±0.20(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature

C90104 - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed

C90104 - Introduction

7-Chloro-1,2,3,4-tetrahydroisoquinoline is an organic compound with the chemical formula C9H10ClN and a molecular weight of 167.63g/mol. The following is a description of its nature, use, preparation and safety information:

Nature:
- 7-Chloro-1,2,3,4-tetrahydroisoquinoline is a colorless or slightly yellow liquid with a special aromatic smell.
-It is soluble in a variety of organic solvents, such as alcohols, ethers and ketones, insoluble in water.
-The compound has a medium vapor pressure and melting point and can be purified by crystallization or distillation.

Use:
- 7-Chloro-1,2,3,4-tetrahydroisoquinoline is an important organic intermediate that can be used to synthesize various drugs and bioactive molecules.
-It has a wide range of applications in the field of medicine, such as for the synthesis of antipsychotic drugs, antidepressants and analgesic drugs.

Preparation Method:
- 7-Chloro-1,2,3,4-tetrahydroisoquinoline can be synthesized by various methods. The commonly used method is to react acyl with isoquinoline, and then chlorinate to obtain the desired product.

Safety Information:
- 7-Chloro-1,2,3,4-tetrahydroisoquinoline is an organic compound with certain toxicity and safe operation methods should be followed.
-Wear appropriate personal protective equipment, such as lab gloves, glasses, and lab coats, during use or handling.
-Avoid touching skin, eyes or inhaling vapors. In case of contact or aspiration, rinse immediately with plenty of water and seek medical assistance if necessary.
-Pay attention to fire sources and static electricity when handling the compound to avoid contact with flammable substances to prevent fire or explosion. It must be operated in a well-ventilated area to avoid steam accumulation.
-During storage, 7-Chloro-1,2,3,4-tetrahydroisoquinoline should be kept away from acids, oxidants and strong oxidizing substances.

Last Update：2024-04-09 02:00:48