CBZ-D-ALLO-ILE-OH - Names and Identifiers
CBZ-D-ALLO-ILE-OH - Physico-chemical Properties
Molecular Formula | C14H19NO4
|
Molar Mass | 265.3 |
Storage Condition | -15°C |
CBZ-D-ALLO-ILE-OH - Introduction
Z-D-allo-Ile-OH . DCHA (Z-D-allo-Ile-OH · DCHA) is an organic compound and a reagent for protecting amino acids. The following is a description of its nature, use, formulation and safety information:
Nature:
-Chemical formula: C23H31NO5
-Molecular weight: 405.50g/mol
-Appearance: White crystalline solid
-Melting point: 105-108°C
-Solubility: Soluble in organic solvents such as acetone, ether, dichloromethane, insoluble in water.
Use:
- Z-D-allo-Ile-OH . DCHA is a reagent used to protect amino acids. By introducing a Cbz group on the amino group of an amino acid, accidental alteration of the amino group in a chemical synthesis reaction can be prevented.
-It is often used in peptide synthesis, especially for the synthesis of peptide sequences with special structures or activities.
Preparation Method:
- Z-D-allo-Ile-OH. The preparation of DCHA usually starts from D-isoleucine, and then reacts with Cbz anhydride for esterification to introduce Cbz protecting group. Finally, DCHA (dichloroformic acid) is reacted with the amino acid to form the corresponding salt.
Safety Information:
- Z-D-allo-Ile-OH . DCHA is less toxic, but should be handled with caution. Avoid contact with skin and eyes, wear protective gloves and glasses if necessary.
-During use, standard laboratory operating procedures should be followed and appropriate ventilation equipment should be used.
-When storing, keep the compound in a dry, cool place away from sources of fire and open flames.
Last Update:2024-04-10 22:29:15