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CEFTAZIDIMEPENTAHYDRATE

Ceftazidime

CAS: 78439-06-2

Molecular Formula: C22H32N6O12S2

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CEFTAZIDIMEPENTAHYDRATE - Names and Identifiers

Name Ceftazidime
Synonyms Ceftazidime
CEFTAZIDIMEPENTAHYDRATE
1-[[(6R,7R)-7-[[(2Z)-(2-AMINO-4-THIAZOLYL)[(1-CARBOXY-1-METHYLETHOXY)IMINO]ACETYL]AMINO]-2-CARBOXY-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-EN-3-YL]METHYL]PYRIDINUMPENTAHYDRATE
1-[[(6r,7r)-7-[[(2z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinumhydroxideinnersalt
CAS 78439-06-2
EINECS 616-626-8

CEFTAZIDIMEPENTAHYDRATE - Physico-chemical Properties

Molecular FormulaC22H32N6O12S2
Molar Mass636.65
Melting Point>1500C (dec.)
Storage Condition2-8°C
Physical and Chemical PropertiesAppearance properties of this product is white or white crystalline powder.

CEFTAZIDIMEPENTAHYDRATE - Risk and Safety

Hazard SymbolsXn - Harmful
Harmful
Risk Codes42/43 - May cause sensitization by inhalation and skin contact.
Safety DescriptionS22 - Do not breathe dust.
S36/37 - Wear suitable protective clothing and gloves.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S37 - Wear suitable gloves.
S24 - Avoid contact with skin.

CEFTAZIDIMEPENTAHYDRATE - Reference

Reference
Show more
1. Zhang Jipei, Tan Hualong, Wei Qinglan, et al. Detection of drug resistance and resistance genes of Escherichia coli isolated from waterfowl in Guangdong province [J]. Chinese Journal of Animal Science and Veterinary Medicine, 2015, 42(9):2487-2492.
2. Zhao, Zhen-Zhu, et al. "Biologically active polyketides and 8, 14-seco-ergosterol from fruit medicines of the ascomycete Daldinia childiae." Phytochemistry 142 (2017): 68-75.https:// doi.org/10.1016/j. Phytochem.6/020

CEFTAZIDIMEPENTAHYDRATE - Correlation between ceftazidime and ciprofloxacin consumption and drug resistance of Acinetobacter baumannii

From Wanfang Medicine

Author:

Luo Yanping ,< a href = "https://xueshu.baidu.com/s?wd=author: (Zhou Weiwei) & tn = SE_baiduxueshu_c1gjeupa & ie = utf-8 & SC _f_para = SC _hilight = person" target = "_blank"> Zhou Weiwei ,< a href = "https://xueshu.baidu.com/s?wd=author: (Xu Yaping) & tn = SE_baiduxueshu_c1gjeupa & ie = utf-8 & SC _f_para = SC _hilight = person" target = "_blank"> Xu Yaping , Zhang Xiuju , Chen Rong ,< a href = "https://xueshu.baidu.com/s?wd=author: (Zhou Guang) & tn = SE_baiduxueshu_c1gjeupa & ie = utf-8 & SC _f_para = SC _hilight = person" target = "_blank"> Zhou Guang

Summary:

objective to investigate the drug resistance of acinetobacter baumannii to 6 antibiotics and the annual dosage of these drugs from 1994 to 2003 in the general hospital of the people's liberation army, and to explore the correlation between drug dosage and drug resistance. Methods Retrospective investigation method, paper diffusion method was used for drug sensitivity test and WHONET5.3 and. EXCEL software analysis, the annual dosage of 6 antibiotics from 1994 to 2003 and the drug resistance of Acinetobacter baumannii to these drugs were analyzed, the frequency of each medicinal drug (DDDs) was calculated, and the correlation between drug resistance rate and drug frequency was analyzed by statistical methods. Results In the past 10 years, the drug resistance rates of Acinetobacter baumannii to 6 antibiotics showed an increasing trend. The maximum increases in the drug resistance rates of ceftazidime and ciprofloxacin were 46.5% and 42.3% respectively. The drug resistance rate of Acinetobacter baumannii to piperacillin was 32.4% in 1994 and increased to 62% in 2003. The drug resistance rate to imipenem was the lowest among the 6 antibiotics. Correlation, the annual dosage of ceftazidime and ciprofloxacin was positively correlated with the change of the resistance rate of Acinetobacter baumannii to these two drugs (r = 0.88,P≤ 0.01 and r = 0.65,P≤ 0.05, respectively), while the resistance of ceftazidime to piperacillin and cefotaxime was significantly correlated (r = 0.82,P≤ 0.01 and r = 0.82,P≤ 0.01, respectively); the use of ciprofloxacin was also correlated with the resistance rates of piperacillin and cefotaxime (r = 0.80,P≤ 0.01 and r = 0.68,P≤ 0.05, respectively). Conclusion The annual dosage of ceftazidime and ciprofloxacin is not only positively correlated with the drug resistance rate of Acinetobacter baumannii to these two antibiotics, but also has significant correlation with the drug resistance of ceftazidime and piperacillin and cefotaxime.

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keywords:

Acinetobacter baumannii drug resistance antibiotics correlation

DOI:

10.3321/j.issn:1005-4529.2005.07.032

cited:

74

Year:

2005

Last Update：2024-01-02 23:10:35

CEFTAZIDIMEPENTAHYDRATE - Flow injection chemiluminescence determination of Ceftazidime

From Titanium Academic

Author:

Wang Jue , Qu Jianying , Zhu Lili , Wang Jinzhong , Wang Yue

Summary:

Under alkaline conditions, ceftazidime has obvious sensitizing effect on the luminol chemiluminescence system catalyzed by gold nanoparticles. Based on this, a chemiluminescence method for the determination of ceftazidime was established. Under the optimized experimental conditions, the linear range of ceftazidime determination by this method is 3.0 × 10-5~5.0 × 10-2g/L, the detection limit is 1.0 × 10-5g/L, and the relative standard deviation is 2.0%(& rho;= 4.0 × 10-3g/L,n = 11), which is used for the determination of ceftazidime content in pharmaceutical preparations, and the average recovery rate is 99%, the results are satisfactory.

keywords:

chemiluminescence flow injection luminol ceftazidime nano gold

DOI:

10.3969/j.issn.1004-4957.2011.01.019

cited:

43

Year:

2011

Last Update：2023-08-16 22:09:50

CEFTAZIDIMEPENTAHYDRATE - Determination of ceftazidime in injection by Fe(2 )-Phenanthroline spectrophotometry

From VIP Journal Professional Edition

Author:

Fang Tingting , sand gull

Summary:

Based on the reduction of Fe ~(3) to Fe ~(2) by ceftazidime, the generated Fe ~(2) forms a red complex with o-phenanthroline, a new method for the determination of ceftazidime by Fe ~(2 )-o-phenanthroline spectrophotometry was established. The concentration of ceftazidime standard solution was linearly related to absorbance in the range of 0.4-10mg, the linear regression equation is △A = 0.1008C(mg/L) 0.07789. The linear correlation coefficient r = 0.9970. The method has been applied to the content analysis of ceftazidime in injections with satisfactory results.

keywords:

spectrophotometry ceftazidime o-phenanthroline

DOI:

10.3969/j.issn.1004-8138.2010.02.055

cited:

44

Year:

2010

Last Update：2023-08-16 22:09:50
CEFTAZIDIMEPENTAHYDRATE
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Hubei YoungXin Pharmaceutical Tech Co.,Ltd.
Product Name: Ceftazidime Monomer Request for quotation
CAS: 78439-06-2
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052 Click to send a QQ message
Wechat: 15671228036
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: Ceftazidime Request for quotation
CAS: 78439-06-2
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: Ceftazidime Pentahydrate (Contain 1 equivalent of Na2CO3 as stabilizer) Visit Supplier Webpage Request for quotation
CAS: 78439-06-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
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