Name | L-Proline compd. with (1S)-1,5-anhydro-1-C-[3-(benzo[b]thien-2-ylmethyl)-4-fluorophenyl]-D-glucitol (1:1) |
Synonyms | CPD1060 l-prolinecompd Ipragliflozin-002-L Azilsartan Impurity 62 (2S,3R,4R,5S,6R)-2-[3-(1-benzothiophen-2-ylmethyl)-4-fluorophenyl]-6-(hydroxymethyl)oxane-3,4,5-triol,(2S)-pyrrolidine-2-carboxylic acid |
CAS | 951382-34-6 |
Molecular Formula | C21H21FO5S.C5H9NO2 |
Molar Mass | 519.58 |
Storage Condition | 2-8°C |
biological activity | Ipragliflozin L-Proline is an orally active selective inhibitor of SGLT2, the IC50 of rat SGLT2 and mouse SGLT2 were 7.38 nM, 6.73 nM and 5.64 nM, respectively. |
Target | Value |
mouse SGLT2 (Cell-free assay) | 5.64 nM |
rat SGLT2 (Cell-free assay) | 6.73 nM |
human SGLT2 (Cell-free assay) | 7.38 nM |