CS-1628
GSK-LSD1 2HCl
CAS: 1431368-48-7
Molecular Formula: C14H20N2
CS-1628 - Names and Identifiers
CS-1628 - Physico-chemical Properties
| Molecular Formula | C14H20N2 |
| Molar Mass | 216.32 |
| Density | 1.07±0.1 g/cm3(Predicted) |
| Boling Point | 347.4±42.0 °C(Predicted) |
| Solubility | Soluble in DMSO |
| Appearance | powder |
| Color | white to beige |
| pKa | 10.14±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Use | GSK-LSD1 2HCl is a specificity irreversible LSD1 inhibitor (IC50: 16 nM). The selectivity of GSK-LSD1 for LSD1 is >1000 fold over other closely related FAD utilizing enzymes (i.e. MAO-A, LSD2, MAO-B). |
| In vitro study | GSK-LSD1 induces gene expression changes in cancer cell lines with average EC50 of < 5 nM and inhibits cancer cell line growth with average EC50 of < 5 nM. |
CS-1628 - Risk and Safety
| WGK Germany | 3 |
CS-1628 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.457 ml | 17.287 ml | 34.573 ml |
| 5 mM | 0.691 ml | 3.457 ml | 6.915 ml |
| 10 mM | 0.346 ml | 1.729 ml | 3.457 ml |
| 5 mM | 0.069 ml | 0.346 ml | 0.691 ml |
Last Update：2024-01-02 23:10:35
CS-1628 - Reference Information
| biological activity | GSK-LSD1 2HCl is an irreversible selective LSD1 inhibitor with an IC50 of 16 nM, the selectivity was more than 1000-fold higher than that of other closely related FAD available enzymes (I. E., LSD2,MAO-A,MAO-B). |
Last Update：2024-04-10 22:29:15
Supplier List
Spot supply
Product Name: GSK-LSD1 2HCl Visit Supplier Webpage Request for quotationCAS: 1431368-48-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: GSK-LSD1 2HCl Visit Supplier Webpage Request for quotationCAS: 1431368-48-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History