CS-2420 - Names and Identifiers
Name | I-CBP 112
|
Synonyms | CS-2420 I-CBP112 I-CBP 112 I-CBP-112 I-CBP 112 I-CBP112, 1640282-31-0 I-CBP112 hydrochloride 1-Propanone, 1-[7-(3,4-dimethoxyphenyl)-2,3-dihydro-9-[[(3S)-1-methyl-3-piperidinyl]methoxy]-1,4-benzoxazepin-4(5H)-yl]- 1-[7-(3,4-Dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-2,3,4,5-tetrahydro-1,4-benzoxazepin-4-yl]propan-1-one
|
CAS | 1640282-31-0
|
CS-2420 - Physico-chemical Properties
Molecular Formula | C27H36N2O5
|
Molar Mass | 468.59 |
Density | 1.129±0.06 g/cm3(Predicted) |
Boling Point | 623.5±55.0 °C(Predicted) |
Appearance | powder |
Color | white to beige |
pKa | 9.07±0.10(Predicted) |
Storage Condition | 2-8°C |
CS-2420 - Risk and Safety
UN IDs | UN 3077 9 / PGIII |
WGK Germany | 3 |
CS-2420 - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 2.134 ml | 10.67 ml | 21.341 ml |
5 mM | 0.427 ml | 2.134 ml | 4.268 ml |
10 mM | 0.213 ml | 1.067 ml | 2.134 ml |
5 mM | 0.043 ml | 0.213 ml | 0.427 ml |
Last Update:2024-01-02 23:10:35
CS-2420 - Reference Information
biological activity | I-CBP112 is an effective selective CBP/p300 inhibitor, and the dissociation constants Kd values for CBP and p300 are 151±6 nM and 167±8 nM respectively. |
target | TargetValue cBP (cell-free say) 151 nm (kd) p300 (cell-free say) 167 nm (kd) |
Target | Value |
CBP
(Cell-free assay)
| 151 nM(Kd) |
p300
(Cell-free assay)
| 167 nM(Kd) |
Last Update:2024-04-09 19:05:04