Molecular Formula | C17H12Cl2N6O4 |
Molar Mass | 435.221 |
Density | 1.65±0.1 g/cm3(Predicted) |
Solubility | DMSO: ≥ 31 mg/mL |
pKa | 3.96±0.40(Predicted) |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
Physical and Chemical Properties | Bioactive Resmetirom (MGL-3196, VIA-3196) is a liver-oriented, orally active and selective thyroid hormone receptor β(THR-β) agonist with EC50 of 0.21 μM, and its selectivity for THR-β is 28 times that of THR-α. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.298 ml | 11.488 ml | 22.977 ml |
5 mM | 0.46 ml | 2.298 ml | 4.595 ml |
10 mM | 0.23 ml | 1.149 ml | 2.298 ml |
5 mM | 0.046 ml | 0.23 ml | 0.46 ml |