CS-2448
TUG-891
CAS: 1374516-07-0
Molecular Formula: C23H21FO3
CS-2448 - Names and Identifiers
| Name | TUG-891 |
| Synonyms | TUG-891 CS-2448 TUG 891 3-(4-{[5-fluoro-2-(4-methylphenyl)phenyl]methoxy}phenyl)propanoic acid 4-[(4-Fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]-benzenepropanoic acid Benzenepropanoic acid, 4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]- |
| CAS | 1374516-07-0 |
CS-2448 - Physico-chemical Properties
| Molecular Formula | C23H21FO3 |
| Molar Mass | 364.41 |
| Density | 1.199±0.06 g/cm3(Predicted) |
| Boling Point | 540.8±50.0 °C(Predicted) |
| Solubility | 10 mM in DMSO |
| pKa | 4.70±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| In vitro study | TUG-891 displays similar signaling properties to the LCFA α-linolenic acid at human FFA4, including stimulation of Ca 2+ mobilization, β-arrestin-1 and β-arrestin-2 recruitment, and extracellular signal-regulated kinase phosphorylation. Activation of human FFA4 by TUG-891 also results in rapid phosphorylation and internalization of the receptor. |
CS-2448 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.744 ml | 13.721 ml | 27.442 ml |
| 5 mM | 0.549 ml | 2.744 ml | 5.488 ml |
| 10 mM | 0.274 ml | 1.372 ml | 2.744 ml |
| 5 mM | 0.055 ml | 0.274 ml | 0.549 ml |
Last Update：2024-01-02 23:10:35
CS-2448 - Reference Information
| biological activity | TUG-891 is an effective, selective long chain free fatty acid (LCFA) receptor 4 (FFA4/GPR120) agonist. |
| target | TargetValue FFA4/GPR120 () |
| Target | Value |
| in vitro study | TUG-891 displays similar signaling properties to the LCFA α-linolenic acid at human FFA4, including stimulation of Ca 2 mobilization, β-arrestin-1 and β-arrestin-2 recruitment, and extracellular signal-regulated kinase phosphorylation. Activation of human FFA4 by TUG-891 also results in rapid phosphorylation and internalization of the receptor. |
Last Update：2024-04-09 22:09:11
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Spot supply
Product Name: TUG-891 Visit Supplier Webpage Request for quotationCAS: 1374516-07-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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