CS-2588
XMD8-87
CAS: 1234480-46-6
Molecular Formula: C24H27N7O2
CS-2588 - Names and Identifiers
CS-2588 - Physico-chemical Properties
| Molecular Formula | C24H27N7O2 |
| Molar Mass | 445.52 |
| Density | 1.283±0.06 g/cm3(Predicted) |
| Solubility | DMSO: ≥ 26 mg/mL |
| pKa | 10.18±0.20(Predicted) |
| Storage Condition | -20℃ |
| In vitro study | XMD8-87 were very effective in inhibiting TNK2 phosphorylation and XMD16-5 and XMD8-87 were able to inhibit phosphorylation of the truncated TNK2 mutation in solid tumors. |
CS-2588 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.245 ml | 11.223 ml | 22.446 ml |
| 5 mM | 0.449 ml | 2.245 ml | 4.489 ml |
| 10 mM | 0.224 ml | 1.122 ml | 2.245 ml |
| 5 mM | 0.045 ml | 0.224 ml | 0.449 ml |
Last Update：2024-01-02 23:10:35
CS-2588 - Reference Information
| biological activity | XMD8-87 is a novel non-receptor tyrosine kinase TNK2 inhibitor, the IC50 for D163E and R806Q mutant TNK2 were 38 nM and 113 nM, respectively. |
| Target | TargetValue TNK2 |
| Target | Value |
| in vitro study | XMD8-87 is very effective in inhibiting TNK2 phosphorylation, both XMD16-5 and XMD8-87 inhibited the phosphorylation of the truncated TNK2 mutation in solid tumors. |
Last Update：2024-04-09 19:05:05
Supplier List
Spot supply
Product Name: XMD8-87 Visit Supplier Webpage Request for quotationCAS: 1234480-46-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: XMD8-87 Visit Supplier Webpage Request for quotationCAS: 1234480-46-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History