CS-2838
SBI-0640756；SBI-756
CAS: 1821280-29-8
Molecular Formula: C23H14ClFN2O2
CS-2838 - Names and Identifiers
CS-2838 - Physico-chemical Properties
| Molecular Formula | C23H14ClFN2O2 |
| Molar Mass | 404.82 |
| Solubility | DMSO : 26 mg/mL (64.23 mM) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| In vitro study | This response is not regulated by mTOR signaling SBI-756 to the combination of disrupting the eIF4F complex. It reduces the growth rate of BRAF-resistant and BRAF-dependent melanomas. SBI-756 also inhibits the AKT and NF-kB signaling pathways, inhibiting the growth of melanoma bearing mutations in NRAS, BRAF, and NF1 in vitro. |
| In vivo study | SBI-756 delay the onset and reduce the incidence of Nras/Ink4a melanoma in vivo. |
CS-2838 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.47 ml | 12.351 ml | 24.702 ml |
| 5 mM | 0.494 ml | 2.47 ml | 4.94 ml |
| 10 mM | 0.247 ml | 1.235 ml | 2.47 ml |
| 5 mM | 0.049 ml | 0.247 ml | 0.494 ml |
Last Update：2024-01-02 23:10:35
CS-2838 - Reference Information
| biological activity | SBI-0640756 is the first inhibitor targeting eIF4G1, which can destroy eIF4F complex. |
| Target | Value |
Last Update：2024-04-10 22:29:15
Supplier List
Product Name: SBI-0640756；SBI-756 Visit Supplier Webpage Request for quotation
CAS: 1821280-29-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 1821280-29-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: SBI-0640756；SBI-756 Visit Supplier Webpage Request for quotation
CAS: 1821280-29-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 1821280-29-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History