CYCLOSAN
hypericin from hypericum perforatum
CAS: 548-04-9
Molecular Formula: C30H16O8
CYCLOSAN - Names and Identifiers
| Name | hypericin from hypericum perforatum |
| Synonyms | CYCLOSAN HYPERICIN Hypericin CYCLO-WERROL MYCOPOPHYRIN HYPERICUM RED HYPERICIN (NATIVE) St.John's Wort Extract Hypericin Hypericum perforatum hypericin from hypericum perforatum 1,3,4,6,8,13-HEXAHYDROXY-10,11-DIMETHYLPHENANTHRO[1,10,9,8-OPQRA]PERYLENE-7,14-DIONE 1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione 1,3,4,6,8,13-HEXAHYDROXY-10,11-DIMETHYLPHENANTHROL(1,10,9,8,OPQRA)PERYLENE-7,14-DIONE |
| CAS | 548-04-9 |
| EINECS | 208-941-0 |
| InChI | InChI=1/C30H16O8/c1-7-3-9(31)19-23-15(7)16-8(2)4-10(32)20-24(16)28-26-18(12(34)6-14(36)22(26)30(20)38)17-11(33)5-13(35)21(29(19)37)25(17)27(23)28/h3-6,31-36H,1-2H3 |
| InChIKey | BTXNYTINYBABQR-UHFFFAOYSA-N |
CYCLOSAN - Physico-chemical Properties
| Molecular Formula | C30H16O8 |
| Molar Mass | 504.44 |
| Density | 1.915±0.06 g/cm3(Predicted) |
| Melting Point | 299-301°C |
| Boling Point | 1020.3±65.0 °C(Predicted) |
| Flash Point | 584.6°C |
| Water Solubility | Soluble in ethanol, dimethyl sulfoxide, methanol, acetone, ethylmethylketone, pyridine and sodium hydroxide. Insoluble in water. |
| Solubility | Soluble in water |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Black powdered crystals (pyridine, recrystallized in methanol solution containing hydrochloric acid) |
| Color | black |
| Merck | 14,4863 |
| BRN | 1917913 |
| pKa | 6.91±0.20(Predicted) |
| Storage Condition | -20°C |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
| Sensitive | Light Sensitive |
| Refractive Index | 2.13 |
| MDL | MFCD00016683 |
| Physical and Chemical Properties | Soluble in water. Hypericin is the main active ingredient of Hypericum perforatum. |
| Use | For the treatment of antidepressant disease, increase immunity |
CYCLOSAN - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R40 - Limited evidence of a carcinogenic effect R43 - May cause sensitization by skin contact |
| Safety Description | S22 - Do not breathe dust. S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | 2811 |
| WGK Germany | 3 |
| RTECS | SF8472000 |
| FLUKA BRAND F CODES | 8 |
| HS Code | 29145090 |
CYCLOSAN - Reference
| Reference Show more | 1. Han Dongxia, Li Yanqin, Yang Peng, Li Binchun. Transformation of phototoxic substances in buckwheat and inhibitory activity of buckwheat phytohormone on human colon cancer cell line HCT-116 [J]. Chinese Journal of Biochemistry and Molecular Biology, 2018,34(12):1317-1324. 2. [IF = 7.46] Fan Lin et al."Aggregation/dispersion conversion of hypericin by nonspatially structured DNA and a fluent Ba2 sensor." Sensor Actuat B- Chem. 2017 Aug;247:19 3. [IF = 10.618] Ting Ye et al."Polarisation perceived G-quadruplex metal sensors with K tolerance." Biosens Bioelectron. 2019 Dec;145:111703 4. [IF = 6.558] Qing Qing Song et al."Binary code, a flexible tool for diagnostic metabolite sequencing of medicinal plants."Anal Chim Acta. 2019 Dec;1088:89 5. [IF=4.411] Jiahuan Yuan et al."Qualitative Analysis and Componential Differences of Chemical Constituents in Taxilli Herba from Different Hosts by UFLC-Triple TOF-MS/MS."Molecules. 2021 Jan;26(21):6373 6. [IF=4.411] Qi Dong et al."Inhibitory Activity and Mechanism Investigation of Hypericin as a Novel α-Glucosidase Inhibitor."Molecules. 2021 Jan;26(15):4566 7. [IF=2.352] Luo Ting et al."Phytochemical composition and potential biological activities assessment of raspberry leaf extracts from nine different raspberry species and raspberry leaf tea."J Berry Res. 2020 Jan;10(2):295-309 8. [IF=4.098] Tong Yang et al."Visible light-driven i-motif-based DNAzymes."Spectrochim Acta A. 2022 Apr;270:120845 9. [IF=5.154] Ying Jiang et al."Isolation of a novel characterized Issatchenkia terricola from red raspberry fruits on the degradation of citric acid and enrichment of flavonoid and volatile profiles in fermented red raspberry juice."Food Science and Human Wellness. 202 |
CYCLOSAN - Reference Information
| introduction | hypericin is an extract of Hypericum perforatum. It was first isolated by humans from Hypericum perforatum perforatum in 1957. It belongs to dianthracene and is the most biologically active substance in Hypericum perforatum. Its appearance is grayish yellow to brown fluidity powder, slightly bitter taste, easy to dissolve in water, and can emit special fragrance, it has the effect of inhibiting the central nervous system and sedation. It can be added to health products to enhance immunity. It is also used as an antidepressant in Europe (especially Germany). |
| effect | hypericin also has a strong antiviral effect, can directly act on swine fever, foot-and-mouth disease and other viruses, and also has a good killing effect on highly pathogenic avian influenza virus. Hypericum perforatum is one of the best-selling herbs in the world in recent years. It mainly contains hyperin, quercetin, chlorogenic acid, caffeic acid, yimanning, hypericin and other ingredients. The content of hypericin in the whole plant of Hypericum perforatum is a few parts per ten thousand. There are certain requirements for its extraction and testing. In the past, methanol extraction method was mostly used. Because methanol is toxic, ethanol extraction is now used to obtain the active ingredients. |
| use | hypericin is a pure antiviral traditional Chinese medicine preparation and is the first choice for prevention and treatment of avian influenza. 1. Viral diseases such as avian influenza, atypical Newcastle disease, branch, throat, bursa of Fabricius, duck plague, duck viral hepatitis, and egg production decline syndrome. 2. High fever, dyspnea, cough, swelling of head and face, purple crown, lack of energy, decreased intake, decreased egg production, and more abnormal egg production caused by avian cold. 3, for swine fever, blue ear disease, parvovirus, viral enteritis, infectious gastroenteritis and immune function decline. 4. Hypericin has the effect of removing retrovirus in vivo and in vitro, and has strong antiviral effect. It has a strong inhibitory effect on the early replication of AIDS (HIV). It can cause programmed death of cancer cells and has anti-cancer effects. It can activate mononuclear phagocytes and has the effect of enhancing immunity. It has a strong killing effect on highly pathogenic H5N1 and H9N2 subtype avian influenza viruses. Antidepression, increase immunity. used to treat antidepressants and increase immunity Hypericin is an extract from Hypericum perforatum L. hypericaceae and is believed to be an antibiotic/antiviral, specifically acting as a kinase inhibitor. |
| indications | 1. regulate the immune function of animal machines, induce the body to produce interferon, enhance the body's immunity, and effectively prevent and treat various diseases of livestock and poultry; 2. against avian influenza and plague fever, infectious bursal disease, spread, throat, fowlpox, hypoglycemia syndrome, egg loss syndrome, infectious encephalomyelitis, duck plague, duck viral hepatitis, duck liver white spot disease, gosling plague, adenovirus and A variety of immunodeficiency viruses caused by single or mixed infection of sick birds with high fever, lethargy and severe decline in feed intake; A large group of explosive snoring, coughing, nasal throwing, sneezing, nasal bleeding and lacrimation, epidemic fluid blocking the trachea, opening the mouth to breathe and mixed with wheezing, head shaking mucus, air bag turbid, thickening, foam-like or cheese-like exudates; feces are yellow, white, green or rice soup loose stools; muscle stomach, glandular stomach edema or bleeding; meat and poultry growth stagnation, there are special effects on the decline of egg production, faded eggs, sand shell eggs, and the increase of deformed eggs. 3. For high fever and anorexia caused by swine fever, circovirus disease, blue ear disease, pseudorabies, infectious gastroenteritis, vesicular disease, etc., dyspnea, cough and panting, nasal fluid flow, muscle tremor, mouth, Hoof blisters or ulceration, even hoof shedding, limping, watery diarrhea and other symptoms are effective. 4. It is suitable for many viral diseases of livestock and poultry, delayed bacterial diseases and complicated diseases caused by mixed infection, which are not cured for a long time, physical decline, malnutrition and ineffective treatment of various drugs. |
Last Update：2024-04-09 21:11:58
Supplier List
Product Name: Hypericin Request for quotation
CAS: 548-04-9
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
CAS: 548-04-9
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Hypericin Visit Supplier Webpage Request for quotationCAS: 548-04-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: Hypericin Request for quotation
CAS: 548-04-9
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
CAS: 548-04-9
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Hypericin Visit Supplier Webpage Request for quotationCAS: 548-04-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History