| Name | Carbodiimide |
| Synonyms | Carbodiimide Carbodilite E-02 |
| Molecular Formula | CH2N2 |
| Molar Mass | 42.03998 |
Carbodiimide is an organic compound. The following is an introduction to the properties, uses, preparation methods, and safety information of carbodiimide:
nature:
-Carbodiimide is a colorless crystalline solid that is soluble in many organic solvents but insoluble in water.
-It can catalyze the formation of amides and has weak acidity and nucleophilicity.
-Carbodiimide undergoes hydrolysis reaction, producing urea and ammonia.
Purpose:
-Carbodiimide is commonly used as an activator to catalyze the synthesis of amides. It can convert acyl chlorides or anhydrides into amides and participate in the activation of hydrocarbons in the substrate.
-In the field of biochemistry, carbodiimide can be used as a coupling reagent between activated amino acids and carboxylic acids for peptide synthesis.
-Carbodiimide can also be used to synthesize polymers such as polyamide and polyimide.
Manufacturing method:
Carbodiimide can be prepared by direct thermal decomposition of amino acid esters, or by reacting amino acid esters with thiourea under alkaline conditions.
Security information:
-Carbodiimide may be irritating to the skin, eyes, and respiratory system in some laboratory operations, and direct contact and inhalation should be avoided.
-When using carbodiimide, attention should be paid to protective measures, such as wearing gloves, latex gloves, and goggles.
-When using carbodiimide to prepare amides, attention should be paid to using appropriate ventilation equipment or operating in the laboratory.