Carfilzomib-d8 - Names and Identifiers
Carfilzomib-d8 - Physico-chemical Properties
Molecular Formula | C40H57N5O7
|
Molar Mass | 719.92 |
Storage Condition | -20°C |
Carfilzomib-d8 - Introduction
Carfilzomib-d8 is an isotopically labeled compound of a drug that is a deuterium-labeled molecule of the dehydrometabolite of Carfilzomib. The following is a description of the nature, use, preparation and safety information of the Carfilzomib-d8:
Nature:
The chemical name of the Carfilzomib-d8 is (2R)-4-Methyl-1-((1S)-1-hydroxy-1-(hydroxyamino)propan-2-yl)-1,2,3, 3-dione. Its molecular formula is C18H6D8N3O4 and its molecular weight is 354.41.
Use:
Carfilzomib-d8 is mainly used in the study of pharmacokinetics, pharmacokinetics and drug interactions. By labeling the hydrogen atoms in the drug as deuterium, the metabolic process of the drug in the body can be traced, and the transformation and clearance of the drug in the body can be understood, so as to evaluate the efficacy and toxicity of the drug.
Method:
The preparation of Carfilzomib-d8 is generally carried out by synthetic organic chemical methods. The method involves deuterium (D) labeling of specific hydrogen atoms in Carfilzomib.
Safety Information:
Since Carfilzomib-d8 is a labeled compound, mainly used for research purposes, detailed information on its toxicity and safety may be limited. When using Carfilzomib-d8 for experiments, you need to follow the laboratory's safe operating procedures, pay attention to personal protective measures, and avoid contact with skin, eyes and respiratory tract. If there is an accident, should immediately take corresponding measures, and seek medical help.
Last Update:2024-04-09 21:04:16