Name | medicagenic acid |
Synonyms | NSC 382024 Catsanogenin Medicogenic acid medicagenic acid (4S)-2β,3β-Dihydroxyolean-12-ene-23,28-dioic acid |
CAS | 599-07-5 |
Molecular Formula | C30H46O6 |
Molar Mass | 502.69 |
Density | 1.23±0.1 g/cm3 (20 ºC 760 Torr) |
Melting Point | 380-382℃ (dec.) |
Boling Point | 635.9±55.0 °C(Predicted) |
Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
Appearance | Powder |
pKa | 4.30±0.70(Predicted) |
Storage Condition | 2-8℃ |
MDL | MFCD02752364 |
Physical and Chemical Properties | Soluble in methanol, ethanol, DMSO and other organic solvents, derived from the roots of leguminous alfalfa Medicago sativa l. |
Overview | Medicago sativa. It is the Trifolium family (Trib. MedicagoL. Plant is one of the most widely distributed and widely used cultivated grasses in the world, and is known as the "King of pasture". The nutritional value of alfalfa is very high, rich in protein, vitamins and minerals, is so far found on human health nutrition one of the most comprehensive. Alfalfa (Medicago sativa L.) originated in the Western countries and was introduced into China from Daye. It has been recorded in the past generations and has a cultivation history of more than two thousand years in China. "Compendium of Materia Medica" recorded: "There is an alfalfa garden in Chang'an, the Northern people are very heavy, the south of the Yangtze River is not food". "The famous Doctor" will be listed as a dish on the goods, said that "bitter, flat, non-toxic, the main security, people", with heat and detoxification, cooling blood, Qi and spleen and kidney. In recent years, more and more researchers have realized its important value in the fields of agriculture, animal husbandry, food and health care and medicine, and gradually began to study alfalfa in depth. |
Application | the saponin component contained in alfalfa exists in various parts of the plant (root, stem, leaf, seeds), especially the root content is the most abundant. So far, there are more than 60 kinds of saponins isolated from alfalfa, and the structural skeletons of the isolated compounds are: Medicago sativa acid type, hederagenin type, hederagenin type, glycocalyx sapogenin type (bayogenin), soybean sapogenin type (soy sapogenol), zanhicacid type. The sugars that make up the triterpenoid saponins are glucose, galactose, xylose, arabinose, rhamnose, glucuronic acid, and carcose. These sugars are mostly pyranose, and there are also furanose. In addition, according to the number of sugar chains in the saponin molecule, it can be divided into monosaccharide chain saponins (mono-saccharide saponins), double-saccharide chain saponins (bis-saccharide saponins) and trisaccharide chain saponins (trisaccharide saponins). |
biological activity | medicinal acid (Castanogenin) is a type of drug that is isolated from Herniaria glabra L. A biologically active triterpenoid pentacyclic glycoside having low inhibitory activity against xanthine oxidase, collagenase, elastase and tyrosinase. |