Acid Benzyl Ester, whose chemical name is acid Benzyl Ester, is an organic compound. It has the following properties and uses:
Nature:
-Appearance: White crystalline or solid
-Molecular formula: C17H19NO3
-Molecular Weight: 285.34
-Melting Point: 88-90°C
-Solubility: Soluble in some organic solvents, such as chloroform, methanol and ethanol
Use:
acid benzyl ester is commonly used as a protecting group in organic synthesis. It is an amido protecting group that protects the amino and hydroxyl functional groups to prevent them from accidental reactions or undesirable side reactions in chemical reactions. It is commonly used as an intermediate in the synthesis of polypeptides, drugs and natural products.
Preparation Method:
The preparation method of acid benzyl ester can be realized by the following steps:
1. Dissolve DL-phenylalaninol in anhydrous methanol.
2. Gradually add benzyl carbonate solution to the solution.
3. As the reaction proceeds, the solution temperature is maintained at 0-5°C.
4. After the reaction is completed, acid benzyl ester product is obtained.
5. The product with higher purity can be obtained by crystallization and filtration.
Safety Information:
Acid Benzyl Ester is a chemical and needs to be kept properly and operated under suitable protective conditions. It may be irritating and toxic, so safe operating procedures should be followed when handling. Avoid contact with skin, eyes and mucous membranes during use. In case of accidental exposure or inhalation, seek medical attention immediately.