Cbz-L-Norleucine

Cbz-L-Norleucine - Names and Identifiers

Name	N-Benzyloxycarbonyl-L-norleucine
Synonyms	Z-Nle-Oh Cbz-L-Norleucine Z-L-Nle-OH (oil) Cbz-L-norleucine BENZYLOXYCARBONYL-L-NORLEUCINE N-Benzyloxycarbonyl-L-norleucine N-Benzyloxycarbonyl-dl-norleucine N-[(Phenylmethoxy)carbonyl]-L-norleucine N-Benzyloxycarbonyl-L-norleucine~Z-Nle-OH L-norleucine, N-[(phenylmethoxy)carbonyl]- (2S)-2-[[(Benzyloxy)carbonyl]amino]hexanoic acid
CAS	39608-30-5
InChI	InChI=1/C14H19NO4/c1-2-3-9-12(13(16)17)15-14(18)19-10-11-7-5-4-6-8-11/h4-8,12H,2-3,9-10H2,1H3,(H,15,18)(H,16,17)/t12-/m0/s1

Cbz-L-Norleucine - Physico-chemical Properties

Molecular Formula	C14H19NO4
Molar Mass	265.3
Density	1.16g/cm³
Melting Point	56-58°C
Boling Point	449.2°C at 760 mmHg
Flash Point	225.5°C
Vapor Presure	7.43E-09mmHg at 25°C
BRN	3210973
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.528
MDL	MFCD00063170

Cbz-L-Norleucine - Risk and Safety

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3

Cbz-L-Norleucine - Introduction

N-Benzyloxycarbonyl-L-norleucine(N-Benzyloxycarbonyl-L-norleucine) is an organic compound with the chemical formula C15H21NO5.

Nature:
-Appearance is a colorless to white solid.
-has high solubility, soluble in ethanol, chloroform and dimethyl sulfoxide and other organic solvents.
-Has a weak acidity.
-is a chiral compound with two enantiomers, D-and L.

Use:
- N-Benzyloxycarbonyl-L-norleucine the protecting group commonly used in organic synthesis, the hydroxyl or amino functional group can be temporarily protected during the synthesis to avoid unnecessary reactions.
-can also be used as a synthetic intermediate in organic synthesis.

Preparation Method:
- N-Benzyloxycarbonyl-L-norleucine can be obtained by the reaction of caprolactam and benzyl chloroformate.
-The specific preparation process is to condense caprolactam and benzylchloroformate under alkaline conditions, and then hydrolyze the produced intermediate under acidic conditions to obtain the target product.

Safety Information:
- N-Benzyloxycarbonyl-L-norleucine is toxic, so care should be taken to avoid inhalation, skin contact or ingestion.
-It should be used in a well-ventilated place and wear appropriate protective measures, such as gloves and goggles.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-When storing and handling, please follow chemical safety regulations.

Last Update：2024-04-10 22:29:15