Chlorodimethoxytriazine - Names and Identifiers
Name | 2-Chloro-4,6-dimethoxy-1,3,5-triazine
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Synonyms | CDMT AKOS 89995 Chlorodimethoxytriazine 2-CHLORO-4,6-DIMETHOXY-TRIAZINE 2-Chloro-4,6-Dimetoxy-1,3,5-Triazine 2-CHLORO 4,6-DIMETHOX 1,3,5-TRIAZINE 2-Chloro-4,6-dimethoxy-1,3,5-triazine 2-CHLORO-4,6-DIMETHOXY-1,3,5-TRIAZINE (CDMT)
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CAS | 3140-73-6
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EINECS | 221-541-0 |
InChI | InChI=1/C5H6ClN3O2/c1-10-4-7-3(6)8-5(9-4)11-2/h1-2H3 |
Chlorodimethoxytriazine - Physico-chemical Properties
Molecular Formula | C5H6ClN3O2
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Molar Mass | 175.57 |
Density | 1.36g/cm3 |
Melting Point | 71-78℃ |
Boling Point | 305.1°C at 760 mmHg |
Flash Point | 138.3°C |
Water Solubility | insoluble |
Vapor Presure | 0.00152mmHg at 25°C |
Appearance | White crystal |
Storage Condition | Room Temprature |
Refractive Index | 1.512 |
MDL | MFCD00075607 |
Use | A stable and highly reactive peptide coupling agent |
Chlorodimethoxytriazine - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 - Wear suitable protective clothing and gloves.
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Chlorodimethoxytriazine - Introduction
2-choro-4, 6-dimethoxy-1,3,5-triazine is a white crystalline powder with the chemical formula C6H6ClN3O2 and a molecular weight of 191.58g/mol. It is a heterocyclic organic compound.
Its main use is as a chemical reagent, especially in N-aryl protection reactions in organic synthesis. It can be used as a protecting group to protect the amine group and can be reduced to the target compound by hydrogenation when necessary.
The preparation method of 2-choro-4, 6-dimethoxy-1,3,5-triazine is relatively simple. A commonly used method is to obtain an intermediate by reacting 2,4, 6-trimethoxy-1, 3,5-triazine with oleoyl chloride, the intermediate is then chlorinated in the presence of hydrochloric acid to give the desired product.
For safety information, 2-choro-4, 6-dimethoxy-1,3,5-triazine needs to be stored in a dry, ventilated place, avoid exposure to light. Wear appropriate personal protective equipment when handling. It may also cause irritation to the eyes, skin and respiratory tract, so use caution. Relevant safe operating procedures and chemical disposal methods should be followed during use or disposal.
Last Update:2024-04-10 22:29:15