Cholest-5-ene-3beta,4beta-diol
4β-Hydroxycholesterol
CAS: 17320-10-4
Molecular Formula: C27H46O2
Cholest-5-ene-3beta,4beta-diol - Names and Identifiers
Cholest-5-ene-3beta,4beta-diol - Physico-chemical Properties
| Molecular Formula | C27H46O2 |
| Molar Mass | 402.65 |
| Density | 1.03±0.1 g/cm3(Predicted) |
| Melting Point | 172-174°C |
| Boling Point | 500.2±30.0 °C(Predicted) |
| Solubility | Insuluble (2.8E-5 g/L) (25 °C) |
| Appearance | Powder |
| Color | White to Pale Beige |
| pKa | 14.32±0.70(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Sensitive | Easily absorbing moisture |
| MDL | MFCD00201408 |
Cholest-5-ene-3beta,4beta-diol - Introduction
4β-Hydroxycholesterol (4β-Hydroxycholesterol) is an important steroid compound, which contains β-hydroxyl and cholesterol skeleton in its chemical structure. The following is a description of its nature, use, preparation and safety information:
Nature:
4β-Hydroxycholesterol is a white crystal or crystalline powder, almost insoluble in water, soluble in ethanol and dichloromethane. It has an absorption peak in the ultraviolet region and is inherently optically active.
Use:
4β-Hydroxycholesterol has important physiological functions in vivo and is an intermediate product of cholesterol metabolism. It acts as a substrate in the cholesterol synthesis pathway, where it is converted to cholesterol through the catalytic action of enzymes. In addition, it is also involved in cholesterol transport, cholesterol esterification and other biological processes.
Method:
4β-Hydroxycholesterol can be synthesized by a variety of methods, one of which is a common method using an oxidation reaction catalyzed by cholesterol acid. By oxidizing cholesterol, its acyl group is oxidized to hydroxyl group, and 4β-Hydroxycholesterol can be obtained.
Safety Information:
The current understanding of the toxicity and safety of 4β-Hydroxycholesterol is limited, so use should comply with appropriate laboratory practices and follow relevant safety operating guidelines. Care should be taken to prevent inhalation, contact with skin and eyes. In addition, the compound should also be stored properly to avoid prolonged exposure to light to avoid degradation.
Nature:
4β-Hydroxycholesterol is a white crystal or crystalline powder, almost insoluble in water, soluble in ethanol and dichloromethane. It has an absorption peak in the ultraviolet region and is inherently optically active.
Use:
4β-Hydroxycholesterol has important physiological functions in vivo and is an intermediate product of cholesterol metabolism. It acts as a substrate in the cholesterol synthesis pathway, where it is converted to cholesterol through the catalytic action of enzymes. In addition, it is also involved in cholesterol transport, cholesterol esterification and other biological processes.
Method:
4β-Hydroxycholesterol can be synthesized by a variety of methods, one of which is a common method using an oxidation reaction catalyzed by cholesterol acid. By oxidizing cholesterol, its acyl group is oxidized to hydroxyl group, and 4β-Hydroxycholesterol can be obtained.
Safety Information:
The current understanding of the toxicity and safety of 4β-Hydroxycholesterol is limited, so use should comply with appropriate laboratory practices and follow relevant safety operating guidelines. Care should be taken to prevent inhalation, contact with skin and eyes. In addition, the compound should also be stored properly to avoid prolonged exposure to light to avoid degradation.
Last Update：2024-04-09 21:54:55
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