Cirsiliol
Cirsiliol
CAS: 34334-69-5
Molecular Formula: C17H14O7
Cirsiliol - Names and Identifiers
| Name | Cirsiliol |
| Synonyms | Cirsiliol CIRSILIOL Crisiliol 3'-Hydroxy-6-methoxygenkwanin 6-Methoxyluteolin 7-methyl ether 6-Hydroxyluteolin-6,7-dimethyl ether 6,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE 6,7-DIMETHOXY-5,3',4'-TRIHYDROXYFLAVONE |
| CAS | 34334-69-5 |
Cirsiliol - Physico-chemical Properties
| Molecular Formula | C17H14O7 |
| Molar Mass | 330.29 |
| Melting Point | 280-281.5℃ (methanol ) |
| Appearance | Yellow powder |
| Color | white to beige |
| Storage Condition | 2-8°C |
| In vitro study | In concentrations from 0.01 to 300 μM, cirsiliol causes concentration-dependent relaxation of rat isolated ileum. Cirsiliol may inhibit Ca 2+ influx but stimulates Ca 2+ release from intracellular stores. Treatment with rhamnetin or cirsiliol reduces the proliferation of NSCLC cells through the suppression of radiation-induced Notch-1 expression. |
| In vivo study | In xenograft mouse model, tumor volume is significantly reduced by combinational treatment with irradiation and rhamnetin or cirsiliol compared with irradiation alone. |
Cirsiliol - Risk and Safety
| WGK Germany | 3 |
| RTECS | DJ3011100 |
Cirsiliol - Reference
| Reference Show more | 1. [IF=3.645] Lu Huang et al."Qualitative and quantitative analysis of chemical components in Eupatorium lindleyanum DC. by ultra-performance liquid chromatography-mass spectrometry integrated with anti-inflammatory activity research."J Sep Sci. 2021 Sep;44(17):3174-31 |
Cirsiliol - Reference Information
| biological activity | cirsiol is a potent and selective inhibitor of 5-lipoxygenase (5-lipoxygenase), and is a competitive low-affinity benzodiazepine receptor ligand. |
Last Update：2024-04-09 21:32:09
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Product Name: Cirsiliol Visit Supplier Webpage Request for quotationCAS: 34334-69-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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