Name | corylin |
Synonyms | Corylin corylin 3-(2,2-dimethylchromen-6-yl)-7-hydroxychromen-4-one 7-hydroxy-2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one 7-Hydroxy-2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one 4H-1-Benzopyran-4-one, 3-(2,2-dimethyl-2H-1-benzopyran-6-yl)-7-hydroxy- |
CAS | 53947-92-5 |
InChI | InChI=1/C20H16O4/c1-20(2)8-7-13-9-12(3-6-17(13)24-20)16-11-23-18-10-14(21)4-5-15(18)19(16)22/h3-11,21H,1-2H3 |
Molecular Formula | C20H16O4 |
Molar Mass | 320.34 |
Density | 1.295±0.06 g/cm3(Predicted) |
Melting Point | 238-239 °C(Solv: acetone (67-64-1); hexane (110-54-3)) |
Boling Point | 527.4±50.0 °C(Predicted) |
Solubility | Soluble in alkali, glacial acetic acid, pyridine, slightly soluble in general organic solvents, insoluble in water. DMSO is recommended for dissolution. |
Appearance | Pale yellow crystalline powder |
pKa | 6.98±0.20(Predicted) |
Storage Condition | 2-8°C |
Physical and Chemical Properties | White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from psoralen fruit. |
Reference Show more | 1. Fan Lingqiu Xinsong Gao Yang et al. Simultaneous determination of 10 components in Psoralea corylifolia L. By HPLC [J]. Journal of Qiqihar Medical College, 2018, 39(16):73-76. 2. Chen, Zhi-Jing, et al. "Dietary total prenylflavonoids from the fruits of psoralea corylifolia L. Prevent age-related cognitive defects and down-regulation Alzheimer's markers in SAMP8 mice." Molecules 23.1 (2018): 196.https://doi.org/10.3390/molecules230 3. [IF = 4.379] Li Kai et al. "Quantitative analysis, pharmacokinetics and metabolomics study for the comprehensive characterization of the salt-processing mechanism of Psoraleae Fructus."Sci Rep-Uk. 2019 Jan;9(1):1-10 4. [IF=3.935] Tiehua Zhang et al."Quantitative structure-activity relationship for estrogenic flavonoids from Psoralea corylifolia."J Pharmaceut Biomed. 2018 Nov;161:129 5. [IF=3.267] Zhi-Jing Chen et al."Dietary Total Prenylflavonoids from the Fruits of Psoralea corylifolia L. Prevents Age-Related Cognitive Deficits and Down-Regulates Alzheimer's Markers in SAMP8 Mice."Molecules. 2018 Jan;23(1):196 6. [IF=4.032] Zhiyue Zhao et al."Development and evaluation studies of Corylin loaded nanostructured lipid carriers gel for topical treatment of UV-induced skin aging."Exp Gerontol. 2021 Oct;153:111499 7. [IF=3.361] Yuhao Zhang et al."An integrated approach for structural characterization of Gui Ling Ji by traveling wave ion mobility mass spectrometry and molecular network."Rsc Adv. 2021 Apr;11(26):15546-15556 |