Molecular Formula | C3H6Cl2O2S |
Molar Mass | 177.05 |
Density | 1.456 g/mL at 25 °C (lit.) |
Boling Point | 70 °C/0.5 mmHg (lit.) |
Flash Point | >230°F |
Solubility | Soluble in dichloromethane, ethyl Acetate and hexane. |
Appearance | Liquid |
Color | Clear colorless to light brown |
BRN | 1754119 |
Storage Condition | 2-8°C |
Sensitive | Lachrymatory |
Refractive Index | n20/D 1.489(lit.) |
Use | Use in the presence of Cinchona alkaloids for the generation and capture of sulfanilamide -5-methyrimidine derivatives with imine and glyoxylic acid to provide chiral sulfamides and sultone. |
Hazard Symbols | C - Corrosive |
Risk Codes | R34 - Causes burns R36/37 - Irritating to eyes and respiratory system. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S24/25 - Avoid contact with skin and eyes. |
UN IDs | UN 3265 8/PG 2 |
WGK Germany | 3 |
RTECS | TZ6670000 |
FLUKA BRAND F CODES | 10-19-21 |
HS Code | 29049090 |
Hazard Note | Corrosive/Lachrymatory |
Hazard Class | 8 |
Packing Group | II |
Raw Materials | Thionyl chloride 1,3-Propane sultone |
3-chloropropane sulfonyl chloride is an important intermediate of medicine, pesticide and dye. Especially in recent years, it has been widely used in the synthesis of anti-hepatitis C Virus drugs, it is an essential intermediate in the synthesis of these drugs, so the research and development of this intermediate has been paid much attention.
overview | 3-chloropropane sulfonyl chloride is an important intermediate of medicine, pesticide and dye, especially in recent years, it has been widely used in the synthesis of anti-hepatitis C virus drugs and is an indispensable intermediate in the synthesis of these drugs, therefore, the research and development of this intermediate has received a lot of attention. |
Use | In the presence of cinchona alkaloids, it is used to generate and capture sulfa-5-pyrimidine with imine and glyoxylic acid Derivatives to provide chiral sulphonactam and sulphonolactone. |