CucurbitacinIIA - Names and Identifiers
CucurbitacinIIA - Physico-chemical Properties
Molecular Formula | C32H50O8
|
Molar Mass | 562.73 |
Density | 1.22 |
Boling Point | 679.1±55.0 °C(Predicted) |
Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
Appearance | White crystalline powder |
pKa | 12.81±0.29(Predicted) |
Storage Condition | 2-8℃ |
MDL | MFCD07781419 |
Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Cucurbitaceae. |
CucurbitacinIIA - Reference
Reference Show more | 1. [IF=3.775] Jie Zhang et al."Cucurbitacin IIa interferes with EGFR-MAPK signaling pathway leads to proliferation inhibition in A549 cells."Food Chem Toxicol. 2019 Oct;132:110654 |
CucurbitacinIIA - Introduction
CucurbitacinIIA is a natural product with the chemical name 5,11, 14-trihydroxysnow bile ketone. It is mainly found in Chinese herbal medicine, such as snow Gall, Lily, etc. Cucurbitacin IIA has the following properties:
Nature:
-Appearance is colorless needle crystal or white crystalline powder.
-Soluble in ethanol, dimethyl sulfoxide and chloroform, insoluble in water.
-It has a bitter taste.
Use:
-cucurbitacin IIA is commonly used in traditional Chinese medicine preparations.
-It has anti-inflammatory, antioxidant, antitumor, antithrombotic, antifibrinolytic and other activities.
Preparation Method:
-The extraction of cucurbitacin IIA usually uses ultrasonic extraction method with alcohol (such as ethanol) as solvent.
-After extraction, cucurbitacin IIA can be obtained through crystallization and purification.
Safety Information:
-Cucurbitacin IIA is a natural product, but it still needs to follow safe operating regulations.
-For contact and inhalation, care should be taken to maintain a well-ventilated laboratory environment.
-Avoid direct contact with skin and eyes, if there is contact, please rinse immediately with water.
-When using cucurbitacin IIA for experiments or preparing drugs, safety assessment and reasonable risk control should be carried out.
It is worth noting that cucurbitacin IIA is a pharmaceutical ingredient. If you need to use it, you should follow the relevant regulations and drug management regulations. Before use, it is recommended to consult a medical professional or pharmacist for advice.
Last Update:2024-04-09 15:16:35