D-(R)-Azetidine-2-Carboxylic - Names and Identifiers
D-(R)-Azetidine-2-Carboxylic - Physico-chemical Properties
Molecular Formula | C4H7NO2
|
Molar Mass | 101.1 |
Density | 1.275±0.06 g/cm3(Predicted) |
Melting Point | 209-211°C |
Boling Point | 242.0±33.0 °C(Predicted) |
Flash Point | 100.1°C |
Solubility | Methanol (Slightly), Methanol (Slightly) |
Vapor Presure | 0.0116mmHg at 25°C |
Appearance | Solid |
Color | White to Off-White |
pKa | 2.35±0.20(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
Stability | Temperature Sensitive - Do Not Heat Above 55°C |
Refractive Index | 1.499 |
D-(R)-Azetidine-2-Carboxylic - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | 22 - Harmful if swallowed
|
Safety Description | 24/25 - Avoid contact with skin and eyes.
|
HS Code | 29339900 |
D-(R)-Azetidine-2-Carboxylic - Introduction
D-Azetidine-2-carboxylic acid(D-Azetidine-2-carboxylic acid) is an organic compound whose chemical formula is C5H7NO2. The following is an introduction to its nature, use, formulation and safety information:
Nature:
D-Azetidine-2-carboxylic acid is a white solid with a bitter taste. It is an enantiomer of the nonenantiomer L-acridine-2-carboxylic acid and can be prepared by chiral synthetic methods. The compound is stable at room temperature.
Use:
D-Azetidine-2-carboxylic acid has certain uses in the field of chemistry and medicine. It is an important chiral intermediate with potential applications in the synthesis of drugs and bioactive molecules. It can be used as a key synthetic step in the synthesis of a wide range of chiral drugs and natural products.
Preparation Method:
The preparation method of D-Azetidine-2-carboxylic acid mainly includes the following steps:
1. Using 1,4-vinylidene dichlorobenzene (1,4-dichlorobenzene) as the starting material, D-acridine-2-methyl ring was obtained by electrophilic substitution reaction.
2. D-acridine -2-methyl ring is converted into D-Azetidine-2-carboxylic acid through a series of chemical reactions.
Safety Information:
D-Azetidine-2-carboxylic the toxicity data of acid is limited, it is generally considered to be a low toxicity compound. Appropriate laboratory safety measures, such as gloves, goggles and laboratory clothing, need to be taken during operation. Avoid contact with skin and eyes, and make sure to operate in a well-ventilated area. Follow proper storage methods and avoid contact with incompatible substances. In case of any discomfort or accident, seek medical help immediately.
Last Update:2024-04-09 15:17:59