D-3-Chlorophenylalanine - Names and Identifiers
D-3-Chlorophenylalanine - Physico-chemical Properties
Molecular Formula | C9H10ClNO2
|
Molar Mass | 199.63 |
Density | 1.336±0.06 g/cm3(Predicted) |
Boling Point | 339.5±32.0 °C(Predicted) |
Appearance | Powder |
Color | White |
pKa | 2.17±0.10(Predicted) |
Storage Condition | Store at 0°C |
D-3-Chlorophenylalanine - Risk and Safety
Hazard Symbols | Xi - Irritant
|
D-3-Chlorophenylalanine - Introduction
3-Chloro-D-phenylalanine is an organic compound with the chemical formula C9H10ClNO2. It belongs to a class of amino acids that contains the structure of D-phenylalanine and has a chlorine atom substituted on the benzene ring. The following is a description of some properties, uses, preparation and safety information about 3-Chloro-D-phenylalanine:
Nature:
-Appearance: Colorless or white solid
-Melting point: about 159-161°C
-Solubility: Slightly soluble in common solvents
-Optically active: with optical properties
Use:
- 3-Chloro-D-phenylalanine is an important intermediate in organic synthesis, which is widely used in the field of drug and pesticide synthesis.
-It can be used as a modeling unit for the synthesis of potential drug molecules and participate in the synthesis of active compounds.
Preparation Method:
There are two common ways to prepare 3-Chloro-D-phenylalanine:
1. through the method of synthesis of chlorophenylalanine, first synthesis of chlorophenylalanine, and then acidification, reduction and other reactions, and finally purified to obtain 3-Chloro-D-phenylalanine.
2. By using a chiral protecting group of D-phenylalanine, such as Boc or Fmoc, and then carrying out a chlorination reaction, the hydrogen atom on the benzene ring is selectively replaced to obtain 3-Chloro-D-phenylalanine.
Safety Information:
- 3-Chloro-D-phenylalanine has little effect on human health under general conditions, but it is still necessary to pay attention to safe operation.
-Avoid inhalation, swallowing or contact with skin and eyes during operation and use to avoid irritation or allergic reactions.
-Prolonged or heavy exposure may be a potential health hazard, so appropriate precautions such as gloves, goggles and respiratory protection should be taken during operation.
-When handling and storing, use containers that meet safety standards, and properly identify and store them.
-When using or disposing of waste, please follow local regulations and avoid pollution to the environment.
Last Update:2024-04-09 20:49:11