D-3-Chlorophenylglycine
4-Chloroindoline
CAS: 41910-64-9
Molecular Formula: C8H8ClN
D-3-Chlorophenylglycine - Names and Identifiers
| Name | 4-Chloroindoline |
| Synonyms | 4-CHLOROINDOLINE 4-Chloroindoline D-3-Chlorophenylglycine 4-Chloro-2,3-dihydro-indole 4-CHLORO-2,3-DIHYDRO-1H-INDOLE 4-Chloro-2,3-dihydro-1H-indole 1H-Indole, 4-chloro-2,3-dihydro- 4-CHLORO-2,3-DIHYDRO-1H-INDOLE HYDROCHLORIDE 4-Chloroindoline 4-Chloro-2,3-dihydro-1H-indole in stock Factory |
| CAS | 41910-64-9 |
| EINECS | 255-586-2 |
| InChI | InChI=1/C8H8ClN/c9-7-2-1-3-8-6(7)4-5-10-8/h1-3,10H,4-5H2 |
D-3-Chlorophenylglycine - Physico-chemical Properties
| Molecular Formula | C8H8ClN |
| Molar Mass | 153.61 |
| Density | 1.214±0.06 g/cm3(Predicted) |
| Boling Point | 135 °C(Press: 10 Torr) |
| Flash Point | 111°C |
| Vapor Presure | 0.0126mmHg at 25°C |
| pKa | 4.26±0.20(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.579 |
D-3-Chlorophenylglycine - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | 25 - Toxic if swallowed |
| Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | 2735 |
| Hazard Class | 8 |
| Packing Group | Ⅲ |
D-3-Chlorophenylglycine - Introduction
4-Chloroindoline(4-Chloroindoline) is an organic compound with the chemical formula C8H6ClN. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 4-Chloroindoline is a colorless to pale yellow crystalline solid.
-Solubility: It is soluble in common organic solvents such as dimethyl sulfoxide (DMSO), methanol and chloroform.
-Melting point: Its melting point is about 80-82°C.
Use:
-Laboratory research: 4-Chloroindoline is commonly used as reagents, catalysts and intermediates in organic synthesis reactions.
-Pharmaceutical field: It may have certain pharmaceutical activity, so it may be used in the field of pharmaceutical research.
Preparation Method:
- 4-Chloroindoline can be obtained by reacting indoline with hydrogen chloride.
-In the first step, indoline is reacted with ferrous chloride and dimethyl sulfoxide (DMSO), and hydrogen chloride gas is introduced under mild conditions. The reaction is generally carried out under an inert atmosphere and the product is isolated from the reaction mixture after cooling.
-In the second step, the product is purified by crystallization or column chromatography.
Safety Information:
- 4-Chloroindoline irritates the skin and eyes. Wear appropriate personal protective equipment such as lab gloves and safety glasses during use.
-This compound is potentially harmful to the environment. Observe relevant environmental regulations during handling and disposal.
Nature:
-Appearance: 4-Chloroindoline is a colorless to pale yellow crystalline solid.
-Solubility: It is soluble in common organic solvents such as dimethyl sulfoxide (DMSO), methanol and chloroform.
-Melting point: Its melting point is about 80-82°C.
Use:
-Laboratory research: 4-Chloroindoline is commonly used as reagents, catalysts and intermediates in organic synthesis reactions.
-Pharmaceutical field: It may have certain pharmaceutical activity, so it may be used in the field of pharmaceutical research.
Preparation Method:
- 4-Chloroindoline can be obtained by reacting indoline with hydrogen chloride.
-In the first step, indoline is reacted with ferrous chloride and dimethyl sulfoxide (DMSO), and hydrogen chloride gas is introduced under mild conditions. The reaction is generally carried out under an inert atmosphere and the product is isolated from the reaction mixture after cooling.
-In the second step, the product is purified by crystallization or column chromatography.
Safety Information:
- 4-Chloroindoline irritates the skin and eyes. Wear appropriate personal protective equipment such as lab gloves and safety glasses during use.
-This compound is potentially harmful to the environment. Observe relevant environmental regulations during handling and disposal.
Last Update：2024-04-09 02:00:46
