Name | D(+)-Mannose |
Synonyms | D-Mannose D-(+)Mannose D(+)-Mannose mannose, pure D-(+)-Mannose D-mannopyranose L-glucopyranose d-[1-18O]Mannose d-[3,4-13C2]Mannose beta-D-mannopyranose d-[1,2,3-13C3]Mannose alpha-D-mannopyranose d-[2,3,4,5,6-13C5]Mannose D-mannose, mixture of anomers d-[UL-12C6]Mannose (13C depleted) d-[1-12C]Mannose (13C depleted at C1) DL-allo-2,3,4,5,6-Pentahydroxy-hexanal |
CAS | 3458-28-4 |
EINECS | 222-392-4 |
InChI | InChI=1/C12H22O11.H2O/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12;/h1,4-12,14-21H,2-3H2;1H2/t4-,5+,6+,7+,8+,9-,10+,11+,12+;/m0./s1 |
InChIKey | WQZGKKKJIJFFOK-ATJJXCEKSA-N |
Molecular Formula | C6H12O6 |
Molar Mass | 180.16 |
Density | 1,539 g/cm3 |
Melting Point | 133-140°C(lit.) |
Boling Point | 232.96°C (rough estimate) |
Specific Rotation(α) | 14 º (589nm, c=10, H2O) |
Water Solubility | 2480 g/L (17 ºC) |
Solubility | Soluble in water (250%), insoluble in ethanol (0.4%), insoluble in ether. |
Appearance | White crystal or powder |
Color | White |
Maximum wavelength(λmax) | ['λ: 260 nm Amax: 0.1', , 'λ: 280 nm Amax: 0.1'] |
Merck | 14,5747 |
BRN | 1564373 |
pKa | 12.08(at 25℃) |
Storage Condition | room temp |
Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
Sensitive | Hygroscopic |
Refractive Index | 1.5730 (estimate) |
MDL | MFCD00064122 |
Physical and Chemical Properties | It is divided into two types: α-type and β-type. A- form is methyl Crystal, melting point 133 ° C.; Β-form is ethyl Crystal, melting point 132 ° C. (decomposition point). Sweet, with a slightly bitter aftertaste. Soluble in water (250%), insoluble in ethanol (0.4%), insoluble in ether. In plants, polysaccharides such as Mannan are mainly present in the form of condensates. The free form is present in the exudates of the coconut shell and the Fraxinus ornus, in addition to trace amounts in the citrus peels, germinated seeds and molasses, etc. |
Use | Used as a Biochemical reagent |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 3 |
TSCA | Yes |
HS Code | 29400010 |
LogP | -2.71 at 25℃ |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
solubility in water (g/100ml) | dissolved grams per 100ml of water: 248g/20 ℃ |
Uses | D-mannose is a carbohydrate that plays an important role in the glycosylation of molecules in various cellular processes. It involves N and O glycosylation of bovine protein products for infant formula. It is also responsible for O-glycosylation of helper T cell-derived cytokine interlukin-17A, an important cell signaling molecule. used in cell culture and molecular biology used as a biochemical reagent sweetener a monosaccharide. |
production method | coconut shell is hydrolyzed with sulfuric acid to obtain α-type mannose. |