DBCO-PEG4-NHS ester
DBCO-NHCO-PEG4-NHS ester
CAS: 2100306-58-7
Molecular Formula: C34H39N3O10
DBCO-PEG4-NHS ester - Names and Identifiers
DBCO-PEG4-NHS ester - Physico-chemical Properties
| Molecular Formula | C34H39N3O10 |
| Molar Mass | 649.69 |
| Storage Condition | -20°C，干燥，密封 |
| In vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
DBCO-PEG4-NHS ester - Reference Information
| biological activity | DBCO-NHCO-PEG4-NHS ester is a PROTAC connection bridge, belonging to PEG class and Alkyl/ether class. DBCO-NHCO-PEG4-NHS ester can be used to synthesize a series of PROTAC molecules. DBCO-NHCO-PEG4-NHS ester is a degradable (cleavable) ADC link bridge for the synthesis of antibody drug conjugates (ADCs). |
| target | Cleavable PEGs Alkyl/ether |
| in vitro research | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Last Update：2024-04-09 21:01:54
