DCLK1-IN-1
DCLK1-IN-1
CAS: 2222635-15-4
Molecular Formula: C26H28F3N7O2
DCLK1-IN-1 - Names and Identifiers
DCLK1-IN-1 - Physico-chemical Properties
| Molecular Formula | C26H28F3N7O2 |
| Molar Mass | 527.54 |
| Density | 1.331±0.06 g/cm3(Predicted) |
| Boling Point | 692.4±65.0 °C(Predicted) |
| pKa | 7.75±0.42(Predicted) |
DCLK1-IN-1 - Reference Information
| biological activity | DCLK1-IN-1 is a selective in vivo compatible chemical probe doublecortin like kinase 1 (DCLK1) domain, which can be combined with DCLK1 and DCLK2, and the corresponding IC50 is 9.5 nM and 31 nM respectively. In the kinase activity assay, the IC50 DCLK1-IN-1 inhibiting DCLK1 and DCLK2 kinases was 57.2 nM and 103 nM, respectively. |
| target | TargetValue dclk1 (cell-free say) 9.5 nm dclk2 (cell-free say) 31 nm dclk1 (kinase say) 57.2 nm dclk2 (kinase say) 103 nm |
| Target | Value |
| DCLK1 (Cell-free assay) | 9.5 nM |
| DCLK2 (Cell-free assay) | 31 nM |
| DCLK1 (kinase assay) | 57.2 nM |
| DCLK2 (kinase assay) | 103 nM |
Last Update：2024-04-09 21:54:55
