Name | Madrasin |
Synonyms | CS-2251 Madrasin DD00107587 DDD00107587 DDD-00107587 4(3H)-Pyrimidinone, 2-[(7-methoxy-4-methyl-2-quinazolinyl)amino]-5,6-dimethyl- |
CAS | 374913-63-0 |
Molecular Formula | C16H17N5O2 |
Molar Mass | 311.34 |
Solubility | 10 mM in DMSO |
Appearance | powder |
Color | white to dark brown |
Storage Condition | 2-8°C |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 3.212 ml | 16.06 ml | 32.119 ml |
5 mM | 0.642 ml | 3.212 ml | 6.424 ml |
10 mM | 0.321 ml | 1.606 ml | 3.212 ml |
5 mM | 0.064 ml | 0.321 ml | 0.642 ml |
biological activity | Madrasin (DDD00107587) is a potent and cell-penetrating pre-mRNA splicing inhibitor. Madrasin can interfere with the early stages of splice assembly and arrest splice assembly on the-complex. |