DIETHYL(TRIMETHYLSILOXYCARBONYLMETHYL)PHOSPHONATE

DIETHYL(TRIMETHYLSILOXYCARBONYLMETHYL)PHOSPHONATE - Names and Identifiers

Name	trimethylsilyl (diethoxyphosphinoyl)acetate
Synonyms	TRIMETHYLSILYL DIETHYLPHOSPHONOACETATE TRIMETHYLSILYL P,P-DIETHYLPHOSPHONOACETATE trimethylsilyl (diethoxyphosphoryl)acetate trimethylsilyl (diethoxyphosphinoyl)acetate Trimethylsilyl (diethoxyphosphinoyl)acetate DIETHYL(2-TRIMETHYLSILOXYCARBONYL)PHOSPHONATE DIETHYL(TRIMETHYLSILOXYCARBONYLMETHYL)PHOSPHONATE DIETHYL (TRIMETHYLSILYLOXYCARBONYLMETHYL)PHOSPHONATE PHOSPHONOACETIC ACID P,P-DIETHYL TRIMETHYLSILYL ESTER Acetic acid, (diethoxyphosphinyl)-, trimethylsilyl ester
CAS	66130-90-3
EINECS	266-171-0
InChI	InChI=1/C9H21O5PSi/c1-6-12-15(11,13-7-2)8-9(10)14-16(3,4)5/h6-8H2,1-5H3

DIETHYL(TRIMETHYLSILOXYCARBONYLMETHYL)PHOSPHONATE - Physico-chemical Properties

Molecular Formula	C9H21O5PSi
Molar Mass	268.32
Density	1.059g/mLat 25°C(lit.)
Boling Point	93°C0.05mm Hg
Flash Point	112°F
Vapor Presure	0.00324mmHg at 25°C
Specific Gravity	1.059
BRN	2371028
Storage Condition	2-8°C
Sensitive	Moisture Sensitive
Refractive Index	n20/D 1.430(lit.)
MDL	MFCD00009080

DIETHYL(TRIMETHYLSILOXYCARBONYLMETHYL)PHOSPHONATE - Risk and Safety

Risk Codes	R11 - Highly Flammable R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	UN 1993 3/PG 2
WGK Germany	3
FLUKA BRAND F CODES	1-10
TSCA	No
HS Code	29310099
Hazard Class	3
Packing Group	III

DIETHYL(TRIMETHYLSILOXYCARBONYLMETHYL)PHOSPHONATE - Introduction

trimethylsilyl (diethoxyphosphinoyl)acetate(trimethylsilyl (diethoxyphosphinoyl)acetate) is an organic compound. Its chemical formula is [(CH3)3Si]2P(O)OCH2COOEt.

Nature:
-Appearance: Colorless or light yellow liquid
-Boiling point: about 130-135 ℃
-Density: about 0.96g/cm³

Use:
trimethylsilyl (diethoxyphosphinoyl)acetate have many applications in organic synthesis, including the following:
1. As a phosphoryl source, it can be used for phosphorylation reaction to generate phosphorylated products.
2. As a silane source, it can be used for silanization reaction to introduce silane groups.
3. as acetyl source, can be used for acetylation reaction.

Preparation Method:
The preparation of trimethylsilyl (diethoxyphosphinoyl)acetate is usually obtained by the following steps:
1. the phosphoryl magnesium dichloride (Ph2PCl2) reacts with butyl dichloroformate to generate diphosphoryl ester (Ph2PO2COCO2Et).
2. reacting diphosphoryl ester with trimethylsilyl chloride to generate trimethylsilyl diphosphoryl ester ((CH3)3SiOP(O)OPPh2).
3. the reaction of trimethylsilane diphosphoryl ester with ethanol to generate trimethylsilyl (diethoxyphosphinoyl)acetate.

Safety Information:
There is less detailed information on the toxicity and safety of trimethylsilyl (diethoxyphosphinoyl)acetate. However, when using any organic compound, you should pay attention to the following safety measures:
-Avoid contact with skin, eyes and respiratory tract.
-Avoid breathing its vapors. If inhaled, quickly remove the victim to fresh air.
-Wear appropriate protective gloves and goggles when using.
-Before use, you should understand and follow the safe operation methods of relevant chemicals in detail.

Last Update：2024-04-10 22:41:03