DIOC18(3)
3,3'-Dioctadecyloxacarbocyanine perchlorate
CAS: 34215-57-1
Molecular Formula: C53H85ClN2O6
DIOC18(3) - Names and Identifiers
| Name | 3,3'-Dioctadecyloxacarbocyanine perchlorate |
| Synonyms | DIO D275 NK 3045 DIOC18(3) 3,3'-dioctadecyloxacarbocyanine 3,3'-dioctadecyloxacarbocyanine N,N'-DIOCTADECYLOXACARBOCYANINE PERCHLORATE 3,3'-Dioctadecyloxacarbocyanine perchlorate BENZOXAZOLIUM, 3-OCTADECYL-2-[3-(3-OCTADECYL-2-BENZOXAZOLINYLIDENE)PROPENYL]-, PERCHLORATE BENZOXAZOLIUM, 3-OCTADECYL-2-[3-(3-OCTADECYL-2(3H)-BENZOXAZOLYLIDENE)-1-PROPENYL]-, PERCHLORATE |
| CAS | 34215-57-1 |
| EINECS | 200-110-4 |
| InChIKey | GFZPJHFJZGRWMQ-UHFFFAOYSA-M |
DIOC18(3) - Physico-chemical Properties
| Molecular Formula | C53H85ClN2O6 |
| Molar Mass | 881.7 |
| BRN | 4122771 |
| Storage Condition | 2-8°C |
| Stability | Stability Stable, but light sensitive. Incompatible with strong oxidizing agents. |
| Physical and Chemical Properties | Bioactive 3,3 '-Dioctadecyloxacarbocyanine perchlorate is a green fluorescent probe for cell membrane. The fluorescence is very weak before entering the cell membrane, and strong fluorescence can only be excited after entering the cell membrane. |
| In vitro study | A fluorescent dialkyl carbocyanine dye (DiOC18(3)) is used to label muscle membranes, and the membranes accessible to the dye were observed by confocal laser scanning microscopy. A loss of cell membrane integrity results from contractile activity, enabling DiOC18(3) staining of internal membranes. The resulting staining pattern is striking and fibers with damaged cell membranes are easily distinguished from uninjured ones. 3,3′-Dioctadecyloxacarbocyanine perchlorate is a cationic oxacarbocyanine dye. The absorption and fluorescence spectra of 3,3'-dioctadecyloxacarbocyanine, a cationic oxacarbocyanine dye have been studied in aqueous and nonaqueous media containing egg phosphatidylcholine (PC) as well as in different solvents of diverse nature. The results show the evidence of complex formation of the dye in the ground and in the excited states with PC. The excited state interaction of the dye with PC suggests the electron transfer from PC to dye and this is supported by photovoltage generation in a photoelectrochemical cell consisting of dye and PC in aqueous medium. |
DIOC18(3) - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | 1479 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 8 |
| HS Code | 29349990 |
| Hazard Class | 5.1 |
| Packing Group | III |
DIOC18(3) - Reference
| Reference Show more | 1. Qiang Li, Liping Wang, Peimin Dai, Xuejun Zeng, Xiaoxiao Qi, Lijun Zhu, Tongmeng Yan, Ying Wang, Linlin Lu, Ming Hu, Xinchun Wang, Zhongqiu Liu, A combined strategy of mass fragmentation, post-column cobalt complexation and shift in ultraviolet absorption 2. [IF=14.919] Wan Mimi et al."Bio-inspired nitric-oxide-driven nanomotor."Nat Commun. 2019 Feb;10(1):1-11 3. [IF=9.229] Meng Wang et al."Erythrocyte Membrane-Wrapped Magnetic Nanotherapeutic Agents for Reduction and Removal of Blood Cr(VI)."Acs Appl Mater Inter. 2020;12(25):28014–28023 4. [IF=6.331] Yangyang Huang et al."Platelet-derived nanomotor coated balloon for atherosclerosis combination therapy."J Mater Chem B. 2020 Jul;8(26):5765-5775 |
DIOC18(3) - Introduction
The 3,3 ′-Dioctadecyloxacarbocyanine perchlorate is a green fluorescent probe for cell membrane. The fluorescence is very weak before entering the cell membrane, and strong fluorescence can only be excited after entering the cell membrane. λex 484 nm; λem 501 nm in MeOH
Last Update：2022-10-16 17:41:10
DIOC18(3) - Reference Information
| biological activity | 3,3 '-Dioctadecyloxacarbocyanine perchlorate is a green fluorescent probe for cell membrane. The fluorescence is very weak before entering the cell membrane, and strong fluorescence can only be excited after entering the cell membrane. |
| in vitro study | a fluorescent dialkyl carbocyanine dye (dioc18 (3)) is used to label muscle membranes, and the membranes accessible to the dye were observed by confocal laser scanning microscopy. a loss of cell membrane integrity results from contractile activity, enabling DiOC18(3) staining of internal membranes. The resulting staining pattern is striking and fibers with damaged cell membranes are easy distinguished from uninjured ones. 3,3 '-Dioctadecyloxacarbocyanine perchlorate is a cationic oxacarbocyanine dye. The absorption and fluorescence spectra of 3,3'-dioctadecyloxacarbocyanine, A cationic oxacarbocyanine dye have been studied in aqueous and nonaqueous media containing egg phosphatidylcholine (PC) as well as in different solvents of diverse nature. The results show the evidence of complex formation of the dye in the ground and in the excited states with PC. The excited state interaction of the dye with PC suggests the electron transfer from PC to dye and this is supported by photovoltage generation in a photoelectrochemical cell consisting dye and PC in aqueous medium. |
Last Update：2024-04-09 21:00:56
DIOC18(3) - In vitro study
A fluorescent dialkyl carbocyanine dye (DiOC18(3)) is used to label muscle membranes, and the membranes accessible to the dye were observed by confocal laser scanning microscopy. A loss of cell membrane integrity results from contractile activity, enabling DiOC18(3) staining of internal membranes. The resulting staining pattern is striking and fibers with damaged cell membranes are easily distinguished from uninjured ones. 3,3′-Dioctadecyloxacarbocyanine perchlorate is a cationic oxacarbocyanine dye. The absorption and fluorescence spectra of 3,3'-dioctadecyloxacarbocyanine, a cationic oxacarbocyanine dye have been studied in aqueous and nonaqueous media containing egg phosphatidylcholine (PC) as well as in different solvents of diverse nature. The results show the evidence of complex formation of the dye in the ground and in the excited states with PC. The excited state interaction of the dye with PC suggests the electron transfer from PC to dye and this is supported by photovoltage generation in a photoelectrochemical cell consisting of dye and PC in aqueous medium.
Last Update：2024-04-09 21:04:16
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Spot supply
Product Name: 3,3'-Dioctadecyloxacarbocyanine perchlorate ('DiO'; DiOC18(3)) Visit Supplier Webpage Request for quotationCAS: 34215-57-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: 3,3'-Dioctadecyloxacarbocyanine perchlorate Request for quotation
CAS: 34215-57-1/28462-56-8
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: 13651600618
WhatsApp: +8613651600618
CAS: 34215-57-1/28462-56-8
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: 13651600618
WhatsApp: +8613651600618
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