DMBX-anabaseine
3-(2,4-dimethoxybenzylidene)anabaseine
CAS: 156223-05-1
Molecular Formula: C19H22Cl2N2O2
DMBX-anabaseine - Names and Identifiers
| Name | 3-(2,4-dimethoxybenzylidene)anabaseine |
| Synonyms | DMBX-anabaseine GTS-21 (DMXB-A) 3-(2,4-dimethoxybenzylidene)anabaseine 3-(2,4)-DiMethoxybenzylidineanabaseine 3-(2,4-Dimethoxy-benzyl)-3,4,5,6-tetrahydro-[2,3']bipyridinyl 3-(2,4-DiMethoxy-benzyl)-3,4,5,6-tetrahydro-[2,3']bipyridinyl Dihydrochloride (3E)-3-[(2,4-Dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3'-Bipyridine dihydrochloride 3-[(3E)-3-[(2,4-dimethoxyphenyl)methylidene]-5,6-dihydro-4H-pyridin-2-yl]pyridine dihydrochloride |
| CAS | 156223-05-1 |
| InChIKey | RPYWXZCFYPVCNQ-RVDMUPIBSA-N |
DMBX-anabaseine - Physico-chemical Properties
| Molecular Formula | C19H22Cl2N2O2 |
| Melting Point | 216-217℃ (decomposition) |
| Solubility | H2O: >5mg/mL |
| Appearance | powder |
| Color | faint yellow to dark yellow |
| Storage Condition | 2-8°C |
| In vitro study | GTS-21 bound to human α4β2 nAChR (K i =20 nM) 100-fold more potently than to humanα7-nAChR, and is 18- and 2-fold less potent than (-)-nicotine at human α4β2 and a7 nAChR, respectively. |
| In vivo study | GTS 21 (4 mg/kg; i.p.; 1, 3, 7, 14 and 21 days) reduces radiation induced histological signs of pulmonary injury. Animal Model: C57BL6 mice were irradiated with 12 Gy to induce a mouse model of Radiation induced lung injury (RILI) Dosage: 4 mg/kg Administration: I.p.; 1, 3, 7, 14 and 21 days Result: Reduces lung inflammatory infiltrate and fibrosis in radiation treated mice. |
DMBX-anabaseine - Risk and Safety
| WGK Germany | 3 |
| RTECS | DW1764860 |
DMBX-anabaseine - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.623 ml | 13.113 ml | 26.226 ml |
| 5 mM | 0.525 ml | 2.623 ml | 5.245 ml |
| 10 mM | 0.262 ml | 1.311 ml | 2.623 ml |
| 5 mM | 0.052 ml | 0.262 ml | 0.525 ml |
Last Update：2024-01-02 23:10:35
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Product Name: GTS-21(DMXB-A) Request for quotation
CAS: 156223-05-1
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CAS: 156223-05-1
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Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: 13651600618
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Product Name: 3-(2,4-dimethoxybenzylidene)anabaseine Visit Supplier Webpage Request for quotationCAS: 156223-05-1
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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