DNQX
Dnqx
CAS: 2379-57-9
Molecular Formula: C8H4N4O6
DNQX - Names and Identifiers
DNQX - Physico-chemical Properties
| Molecular Formula | C8H4N4O6 |
| Molar Mass | 252.14 |
| Density | 1.6919 (rough estimate) |
| Melting Point | >300°C |
| Boling Point | 395.32°C (rough estimate) |
| Solubility | Soluble in DMSO |
| Appearance | Pale yellow solid. |
| Color | Off-White to Light Yellow |
| pKa | 7.68±0.20(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Stability | Store in freezer at -20°C |
| Refractive Index | 1.6700 (estimate) |
| In vitro study | DNQX selectively depolarizes thalamic reticular nucleus (TRN) neurons. |
| In vivo study | DNQX, a specific AMPA receptor antagonist, given as either a 5 mg/kg or 10 mg/kg intraperitoneal dose or into the lateral cerebral ventricle (5 μl of 0.5 mg/ml) significantly diminished PCP (40 mg/kg) and ketamine (80, 100, 120 mg/kg) hsp70 induction in the posterior cingulate and retrosplenial cortex. |
DNQX - Risk and Safety
| WGK Germany | 3 |
DNQX - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.966 ml | 19.83 ml | 39.661 ml |
| 5 mM | 0.793 ml | 3.966 ml | 7.932 ml |
| 10 mM | 0.397 ml | 1.983 ml | 3.966 ml |
| 5 mM | 0.079 ml | 0.397 ml | 0.793 ml |
Last Update：2024-01-02 23:10:35
DNQX - Reference Information
| biological activity | DNQX (FG 9041), is a quinoxaline derivative, is a selective, highly competitive non-NMDA glutamate receptor (non-NMDA glutamate receptor) antagonists (IC50 of 0.5, 2 and 40 μm for AMPA, kainate and NMDA receptors, respectively). |
| Target | AMPA receptor. |
Last Update：2024-04-09 21:11:58
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Spot supply
Product Name: Dnqx Visit Supplier Webpage Request for quotationCAS: 2379-57-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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