DRB18 - Names and Identifiers
DRB18 - Physico-chemical Properties
| Molecular Formula | C22H23ClN2O2
|
| Molar Mass | 382.88 |
| Storage Condition | -20℃ |
| Use | DRB18 is a potent pan-inhibitor of glucose transporter (GLUT). DRB18 alters energy-related metabolism in A549 cells by altering the abundance of metabolites in glucose-related pathways. DRB18 can eventually lead to cell arrest in G1/S phase, increasing oxidative stress and necrotic cell death. DRB18 has anti-tumor activity. |
| Target | GLUT |
DRB18 - Reference
| Reference Show more | 1. Shriwas P, Roberts D, Li Y, et al. A small-molecule pan-class I glucose transporter inhibitor reduces cancer cell proliferation in vitro and tumor growth in vivo by targeting glucose-based metabolism. Cancer Metab. 2021;9(1):14. Published 2021 Mar 26. |
DRB18 - Preparation solution concentration reference
| | 1mg | 5mg | 10mg |
|---|
| 1 mM | 2.612 ml | 13.059 ml | 26.118 ml |
| 5 mM | 0.522 ml | 2.612 ml | 5.224 ml |
| 10 mM | 0.261 ml | 1.306 ml | 2.612 ml |
| 5 mM | 0.052 ml | 0.261 ml | 0.522 ml |
Last Update：2024-01-02 23:10:35
DRB18 - Reference Information
| biological activity | DRB18 is a pan-GLUT (glucose transport) inhibitor, the growth and proliferation of several cancer types can be inhibited with high activity. |
| Target | Value |
Last Update：2024-04-09 21:00:56
