Name | DISUCCINIMIDYL GLUTARATE |
Synonyms | DG1 DSG CDHF4 DSG crosslinker DISUCCINIMIDYL GLUTARATE DI(N-SUCCINIMIDYL) GLUTARATE N,N'-DISUCCINIMIDYL GLUTARATE Di(N-hydroxysucciniMidyl) glutarate Anti-DSG1 antibody produced in goat 2,5-Pyrrolidinedione, 1,1'-[(1,5-dioxo-1,5-pentanediyl)bis(oxy)]bis- |
CAS | 79642-50-5 |
InChI | 1S/C13H14N2O8/c16-8-4-5-9(17)14(8)22-12(20)2-1-3-13(21)23-15-10(18)6-7-11(15)19/h1-7H2 |
InChIKey | LNQHREYHFRFJAU-UHFFFAOYSA-N |
Molecular Formula | C13H14N2O8 |
Molar Mass | 326.26 |
Density | 1.53±0.1 g/cm3(Predicted) |
Melting Point | 168-172 °C |
Boling Point | 485.1±55.0 °C(Predicted) |
Water Solubility | Soluble in dimethylsulfoxide and dimethylformamide. Partially soluble in water. |
Solubility | DMSO (Sparingly, Sonicated), Methanol (Slightly, Sonicated) |
Appearance | Solid |
Color | White to Off-White |
BRN | 8575145 |
Storage Condition | -20°C |
Stability | Hygroscopic, Moisture Sensitive, Unstable in Aqueous Solution |
Sensitive | Moisture Sensitive |
Use | storage: 0-4℃ for short term (days to weeks), or -20℃ for long term (months). For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. |
In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10-21 |
HS Code | 29280000 |
biological activity | DSG Crosslinker is a cleavable ADC linker, for synthesis can be used for the synthesis of antibody conjugated drugs (ADC). |