Name | trp-ala-gly-gly-asp-ala-ser-gly-glu |
Synonyms | DSIP Dsip WAGGDASGE EMIDELTIDE SLEEP INDUCING PEPTIDE DELTA SLEEP INDUCING PEPTIDE DELTA SLEEP-INDUCING PEPTIDE 4H2O TRP-ALA-GLY-GLY-ASN-ALA-SER-GLY-GLU TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU trp-ala-gly-gly-asp-ala-ser-gly-glu TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU 4H2O tryptophylalanylglycylglycyl-alpha-aspartylalanylserylglycylglutamic acid L-tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid |
CAS | 62568-57-4 |
EINECS | 211-519-9 |
InChI | InChI=1/C35H48N10O15/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60) |
InChIKey | ZRZROXNBKJAOKB-GFVHOAGBSA-N |
Molecular Formula | C35H48N10O15 |
Molar Mass | 848.82 |
Density | 1.458±0.06 g/cm3(Predicted) |
Boling Point | 1522.7±65.0 °C(Predicted) |
Flash Point | 874.7°C |
Water Solubility | Soluble in water at 0.5mg/ml |
Vapor Presure | 0mmHg at 25°C |
pKa | 3.18±0.10(Predicted) |
Storage Condition | −20°C |
Refractive Index | 1.612 |
MDL | MFCD00076883 |
Use | Sedative |
In vivo study | In rabbit infused with δ-Sleep Inducing Peptide (DSIP), the spindle activity is increased, and heart and respiration rate are moderately decreased. δ-Sleep Inducing Peptide (DSIP) may act as a programming modulator at supra-operational level rather than as a transmitter at operational level. δ-Sleep Inducing Peptide (DSIP; 40 μg/kg, i.p.) increases catalase and superoxide dismutase (SOD) activities and malonic dialdehyde (MDA) concentration in the liver homogenate of rats subjected to acute stress, but the opposite effects are observed at 120, and 360 μg/kg. |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |