DSPE-PEG-COOH

DSPE-PEG-COOH - Names and Identifiers

Name	DSPE-PEG-COOH
Synonyms	DSPE-PEG-COOH DSPE-PEG2000-COOH DSPE-PEG-2K-CH2COOH DSPE-PEG(2000) Carboxylic Acid 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000] (aMMoniuM salt)
CAS	474922-20-8

DSPE-PEG-COOH - Physico-chemical Properties

Molecular Formula	C134H267N2O57P
Molar Mass	2849.5071
Storage Condition	-20℃

DSPE-PEG-COOH - Introduction

DSPE-PEG-COOH(DSPE-PEG-COOH) is a kind of bioactive molecule with special structure. It consists of two parts: a bisamide group and glycosyl methylethylenediamine (PEG) chain at the tail of the phospholipid, and a carboxyl functional group at the head.

DSPE-PEG-COOH have some notable properties and uses. First of all, it has good water solubility and can help dissolve water-insoluble substances. Secondly, the presence of PEG chains confers excellent biocompatibility to the DSPE-PEG-COOH, which can reduce the immunogenicity of other substances to it. In addition, it has good biodispersibility and can be used to stabilize the surface modification of nanoparticles to improve the stability and biocompatibility of nanoparticles.

In the preparation of DSPE-PEG-COOH, a common method is to react PEG and carboxyl-containing molecules (such as polyacrylic acid or hyaluronic acid) with DSPE to form a PEG chain with carboxyl groups at the end. The preparation process requires certain chemical laboratory facilities and techniques.

When using the DSPE-PEG-COOH, you need to pay attention to its safety. Although ingredients such as PEG and phospholipids are often present in organisms, purity and quality should be ensured before use to avoid possible contamination. In addition, for specific applications, the properties and characteristics of the compound should be carefully understood, and relevant laboratory practices and safety precautions should be observed.

Last Update：2024-04-09 20:52:54

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