Desmethyl-enzalutamide
Enzalutamide Carboxylic Acid Metabolite (M1)
CAS: 1242137-15-0
Molecular Formula: C20H13F4N3O3S
Desmethyl-enzalutamide - Names and Identifiers
Desmethyl-enzalutamide - Physico-chemical Properties
| Molecular Formula | C20H13F4N3O3S |
| Molar Mass | 451.39 |
| Density | 1.59±0.1 g/cm3(Predicted) |
| Melting Point | 210-212°C |
| Boling Point | 590.2±60.0 °C(Predicted) |
| Solubility | DMSO (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | White |
| pKa | 2.94±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Stability | Light Sensitive |
| In vitro study | Enzalutamide is converted into its major metabolites, N-desmethyl enzalutamide and carboxylic acid enzalutamide, by cytochrome P450 (CYP) 3A4/5 and CYP2C8, respectively. N-desmethyl enzalutamide has clinically relevant anti-androgen capacities similar to enzalutamide, whereas carboxylic acid enzalutamide is inactive. |
Desmethyl-enzalutamide - Introduction
Enzalutamide carboxylic acid (MDV3100 carboxylic acid) is an inactive metabolite of Enzalutamide (MDV3100). Enzalutamide are androgen receptor (AR) antagonists.
Last Update：2022-10-16 17:31:12
Desmethyl-enzalutamide - Reference Information
| Use | enzalutamide carboxylic acid is a carboxylic acid amine organic substance, which can be used as an impurity reference substance. |
| biological activity | Enzalutamide carbonic acid (MDV3100 carbonic acid) is an inactive metabolite of Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist. |
Last Update：2024-04-09 21:21:28
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Product Name: Enzalutamide Impurity 1 Visit Supplier Webpage Request for quotationCAS: 1242137-15-0
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple SpecificationsSpot supply
Product Name: Enzalutamide Carboxylic Acid Metabolite (M1) Visit Supplier Webpage Request for quotationCAS: 1242137-15-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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