Molecular Formula | C13H8O6
|
Molar Mass | 260.2 |
Density | 1.766 |
Melting Point | 317℃ |
Boling Point | 605.6±55.0 °C(Predicted) |
Solubility | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
Appearance | Yellow crystalline powder |
pKa | 6.54±0.20(Predicted) |
Storage Condition | 2-8℃ |
MDL | MFCD01741488 |
Physical and Chemical Properties | Yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents. |
In vitro study | 1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) attenuates lipopolysaccharide-induced nitric oxide release and proinflammatory cytokine expression in RAW264.7 cells. |
In vivo study | 1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin; orally; 5, 10, 20 mg/kg; 12 days) can inhibit trinitrobenzenesulfonic acid (TNBS)-induced ulcerative colitis (UC), reducing inflammatory response and alleviate colon muscle spasm. |