Di-tert-butyl(1-methyl-2,2-diphenylcyclopropyl)phosphine
Di-tert-butyl(1-methyl-2,2-diphenylcyclopropyl)phosphine
CAS: 742103-27-1
Molecular Formula: C24H33P
Di-tert-butyl(1-methyl-2,2-diphenylcyclopropyl)phosphine - Names and Identifiers
Di-tert-butyl(1-methyl-2,2-diphenylcyclopropyl)phosphine - Physico-chemical Properties
| Molecular Formula | C24H33P |
| Molar Mass | 352.49 |
| Melting Point | 87-91°C |
| Boling Point | 427.3±45.0 °C(Predicted) |
| Appearance | solid |
| Color | white to pale yellow |
| Storage Condition | Room Temprature |
| Sensitive | air sensitive, store cold |
Di-tert-butyl(1-methyl-2,2-diphenylcyclopropyl)phosphine - Risk and Safety
| WGK Germany | 3 |
Di-tert-butyl(1-methyl-2,2-diphenylcyclopropyl)phosphine - Introduction
Di-tert-butyl(1-methyl-2, 2-diphenylcycloprocyl) phosphine is an organophosphorus compound with the chemical formula C24H31P. The following is a description of its nature, use, preparation and safety information:
Nature:
1. appearance: Di-tert-butyl(1-methyl-2, 2-diphenylcyclopyl) is phosphine as a colorless to light yellow liquid.
2. Solubility: Soluble in common organic solvents, such as ether, dimethylformamide, etc.
Use:
1. catalyst: Di-tert-butyl(1-methyl-2, 2-diphenylcyclopyl) phosphine can be used as a ligand of asymmetric catalyst and participate in various organic synthesis reactions, such as asymmetric addition, asymmetric hydrogenation, asymmetric reduction, etc.
2. Organic synthesis: It can also be used as a reagent to participate in other organic synthesis reactions, such as nucleophilic substitution reactions, the reduction of carbonyl compounds, etc.
Preparation Method:
Di-tert-butyl(1-methyl-2, 2-diphenylcyclopyl) phosphine can be prepared by different synthetic routes. A common preparation method is to react the corresponding cyclopropyl bromide with phenylphosphine, and then obtain the target product through appropriate reaction conditions.
Safety Information:
1. Di-tert-butyl(1-methyl-2, 2-diphenylcyclopyl) phosphine has certain toxicity, and it is necessary to strictly abide by the laboratory safety operation specifications when used.
2. Avoid contact with skin and eyes during operation, and wear protective gloves and goggles if necessary.
3. Storage should be away from fire and oxidant, storage temperature should be below minus 20 degrees Celsius, and keep the container sealed.
Nature:
1. appearance: Di-tert-butyl(1-methyl-2, 2-diphenylcyclopyl) is phosphine as a colorless to light yellow liquid.
2. Solubility: Soluble in common organic solvents, such as ether, dimethylformamide, etc.
Use:
1. catalyst: Di-tert-butyl(1-methyl-2, 2-diphenylcyclopyl) phosphine can be used as a ligand of asymmetric catalyst and participate in various organic synthesis reactions, such as asymmetric addition, asymmetric hydrogenation, asymmetric reduction, etc.
2. Organic synthesis: It can also be used as a reagent to participate in other organic synthesis reactions, such as nucleophilic substitution reactions, the reduction of carbonyl compounds, etc.
Preparation Method:
Di-tert-butyl(1-methyl-2, 2-diphenylcyclopyl) phosphine can be prepared by different synthetic routes. A common preparation method is to react the corresponding cyclopropyl bromide with phenylphosphine, and then obtain the target product through appropriate reaction conditions.
Safety Information:
1. Di-tert-butyl(1-methyl-2, 2-diphenylcyclopyl) phosphine has certain toxicity, and it is necessary to strictly abide by the laboratory safety operation specifications when used.
2. Avoid contact with skin and eyes during operation, and wear protective gloves and goggles if necessary.
3. Storage should be away from fire and oxidant, storage temperature should be below minus 20 degrees Celsius, and keep the container sealed.
Last Update：2024-04-10 22:29:15
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Product Name: Di-tert-butyl(1-methyl-2,2-diphenylcyclopropyl)phosphine Request for quotationCAS: 742103-27-1
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